Progress in hepatectomy for hepatocellular carcinoma and peri-operation management

被引:13
作者
Chen, Hao [1 ,2 ]
Jia, Weidong [1 ,2 ]
机构
[1] Univ Sci & Technol China, Affiliated Hosp USTC 1, Dept Hepat Surg, Div Life Sci & Med, Hefei 230001, Anhui, Peoples R China
[2] Anhui Prov Key Lab Hepatopancreatobiliary Surg, Hefei 230001, Anhui, Peoples R China
关键词
Enhanced recovery after surgery; Hepatectomy; Hepatocettutar carcinoma; Precision medicine; Treatment; INTERMITTENT PRINGLE MANEUVER; RANDOMIZED-CLINICAL-TRIAL; LIVER-FUNCTION TESTS; OF-THE-ART; INDOCYANINE GREEN; HEPATIC RESECTION; INITIAL-EXPERIENCE; ENHANCED RECOVERY; HARMONIC SCALPEL; PD-1; BLOCKADE;
D O I
10.1016/j.gendis.2020.02.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The global incidence of liver cancer continues to grow. Liver cancer, especially hepatocellular carcinoma, has high recurrence and mortality rates. Here, we review the past decade's diagnostic, therapeutic, and management strategies for hepatocellular carcinoma, and summarize new patient management approaches, including enhanced recovery after surgery, targeted therapy, and immunotherapy. We compare traditional and innovative management methods, which comprise developments in precision medicine, and consider their limitations. Ongoing innovation and technological advances enable surgeons to gain deeper understandings of the multidimensionality of hepatocellular carcinoma, thereby promoting the continuous development of precision therapy. Copyright (C) 2020, Chongqing Medical University. Production and hosting by Elsevier B.V.
引用
收藏
页码:320 / 327
页数:8
相关论文
共 89 条
[41]   ALBI and PALBI grade predict survival for HCC across treatment modalities and BCLC stages in the MELD Era [J].
Liu, Po-Hong ;
Hsu, Chia-Yang ;
Hsia, Cheng-Yuan ;
Lee, Yun-Hsuan ;
Chiou, Yi-You ;
Huang, Yi-Hsiang ;
Lee, Fa-Yauh ;
Lin, Han-Chieh ;
Hou, Ming-Chih ;
Huo, Teh-Ia .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2017, 32 (04) :879-886
[42]  
Liu R., 2019, WORLD J GASTROENTERO, V25, P1432, DOI [10.3748/wjg.v25.i12.1432, DOI 10.3748/WJG.V25.I12.1432]
[43]   Insulin resistance and elective surgery [J].
Ljungqvist, O ;
Nygren, J ;
Thorell, A .
SURGERY, 2000, 128 (05) :757-760
[44]   Prognosis of hepatocellular carcinoma:: The BCLC staging classification [J].
Llovet, JM ;
Brú, C ;
Bruix, J .
SEMINARS IN LIVER DISEASE, 1999, 19 (03) :329-338
[45]   Novel advancements in the management of hepatocellular carcinoma in 2008 [J].
Llovet, Josep M. ;
Bruix, Jordi .
JOURNAL OF HEPATOLOGY, 2008, 48 :S20-S37
[46]   Molecular therapies and precision medicine for hepatocellular carcinoma [J].
Llovet, Josep M. ;
Montal, Robert ;
Sia, Daniela ;
Finn, Richard S. .
NATURE REVIEWS CLINICAL ONCOLOGY, 2018, 15 (10) :599-616
[47]  
Llovet JM, 2016, NAT REV DIS PRIMERS, V2, DOI [10.1038/nrdp.2016.18, 10.1038/nrdp.2016.19]
[48]   Recent Progress in Understanding, Diagnosing, and Treating Hepatocellular Carcinoma [J].
Maluccio, Mary ;
Covey, Anne .
CA-A CANCER JOURNAL FOR CLINICIANS, 2012, 62 (06) :394-399
[49]   Prospective evaluation of Pringle maneuver in hepatectomy for liver tumors by a randomized study [J].
Man, K ;
Fan, ST ;
Ng, IOL ;
Lo, CM ;
Liu, CL ;
Wong, J .
ANNALS OF SURGERY, 1997, 226 (06) :704-711
[50]   Effects of the intermittent Pringle manoeuvre on hepatic gene expression and ultrastructure in a randomized clinical study [J].
Man, K ;
Lo, CM ;
Liu, CL ;
Zhang, ZW ;
Lee, TKW ;
Ng, IOL ;
Fan, ST ;
Wong, J .
BRITISH JOURNAL OF SURGERY, 2003, 90 (02) :183-189