Enantioselective synthesis of the bicyclo[4.3.0]nonane ring system of the pinguisane-type sesquiterpenoids via a Bronsted acid promoted transannular enol alkylation

被引：12

作者：

Clarke, PA ^{[1
]}

Black, RJG ^{[1
]}

Blake, AJ ^{[1
]}

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 09期

基金：

英国工程与自然科学研究理事会;

关键词：

pinguisane sesquiterpenoids; transannular cyclisations; enol alkylation; Bronsted acid; vicinal quaternary centres;

D O I：

10.1016/j.tetlet.2005.12.084

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The bicyclo[4.3.0]nonane ring system of the pinguisane-type sesquiterpenoid natural products, including the vicinal quaternary stereocentres, has been synthesised as a single enantiomer via a novel Bronsted acid promoted transannular alkylation of an enol with an unactivated alkene. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：1453 / 1455

页数：3

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