Late recurrence of sigmoid carcinoma mimicking primary vulvar cancer: case report and review of the literature

被引：0

作者：

Pabuccu, Emre ^{[1
]}

Tolunay, Harun Egemen ^{[1
]}

Kocbulut, Evren ^{[1
]}

Taskin, Salih ^{[1
]}

Ortac, Firat ^{[1
]}

Sertcelik, Ayse ^{[2
]}

Sasmaz, Aysegul ^{[2
]}

Savas, Berna ^{[2
]}

机构：

[1] Ankara Univ, Tip Fak, Kadin Hastaliklari & Dogum Anabilim Dali, TR-06100 Ankara, Turkey

[2] Ankara Univ, Sch Med, Dept Pathol, TR-06100 Ankara, Turkey

来源：

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY | 2012年 / 5卷 / 06期

关键词：

Colon; immunohistochemistry; metastasis; sigmoid; vulva; COLORECTAL-CANCER; UNKNOWN PRIMARY; METASTASES; ADENOCARCINOMA; CYTOKERATIN-20; SECONDARY; TUMORS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective: To demonstrate a unique case report about late and isolated vulvar metastasis of sigmoid adeno-carcinoma with review of the literature. Material-method: 57 year old postmenopausal patient with prior sigmoid colon cancer history was admitted with isolated vulvar mass. Immunohistochemistry (IHC) and KRAS gen mutation analysis following surgery were performed to discriminate the metastasis from a vulvar primary malignancy. Further imaging techniques were also performed to exclude additional tumours. Results: Immunohistochemistry (IHC) and KRAS gene mutation analysis revealed isolated metastasis of the colonic adeno-carcinoma in the vulva. Conclusion: Isolated and late occurring vulvar metastasis of colonic origin is very unusual. Careful evaluation and IHC is useful for such cases.

引用

页码：609 / 613

页数：5

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