Base catalyzed reaction of 1,4-dithiane-2,5-diol with α-oxoketene dithioacetals: a new general method for the synthesis of 2-methylthio-3-aroyl/heteroaroyl thiophenes

被引：18
作者：
Kumara, C. S. Pradeepa [1 ,2 ]
Gowda, G. Byre [1 ,2 ]
Kumar, K. S. Vinay [1 ]
Ramesh, N. [2 ]
Sadashiva, M. P. [1 ]
Junjappa, H. [2 ]
机构：
[1] Univ Mysore, Dept Studies Chem, Mysore 570006, Karnataka, India
[2] REVA Inst Sci & Management, Dept Chem, Bengaluru 560064, India
来源：
TETRAHEDRON LETTERS | 2016年 / 57卷 / 38期
关键词：
alpha-Oxoketenedithio acetals; 1,4-Dithiane-2,5-diol; Mercapto acetaldehyde; DERIVATIVES;
D O I：
10.1016/j.tetlet.2016.08.033
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The alpha-oxoketene dithioacetals and 1,4-dithiane-2,5-diol a dimer of mercapto acetaldehyde, react in the presence of anhydrous potassium carbonate in boiling ethanol to yield the corresponding 2-(methylthio)-3-aroyl/heteroaroyl thiophenes in 55-70% overall yields. (C) 2016 Elsevier Ltd. All rights reserved.
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收藏
页码：4302 / 4305
页数：4
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