Facile Synthesis of Thioamides via P2S5-Mediated Beckmann Rearrangement of Oximes

被引：10

作者：

Li Jiangsheng ^{[1
]}

Cheng Chao ^{[1
]}

Zhang Xinrui ^{[1
]}

Li Zhiwei ^{[1
]}

Cai Feifei ^{[1
]}

Xue Yuan ^{[1
]}

Liu Weidong ^{[1
]}

机构：

[1] Changsha Univ Sci & Technol, Hunan Prov Key Lab Mat Protect Elect Power & Tran, Sch Chem & Biol Engn, Changsha 410114, Hunan, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2012年 / 30卷 / 08期

关键词：

thioamides; oximes; phorphorus pentasulfide; Beckmann rearrangement; iminocarbocation; BIOLOGICAL-ACTIVITIES; TRIAZOLE COMPOUNDS; LAWESSONS REAGENT; KINDLER REACTION; KETOXIMES; NITRILES; MILD;

D O I：

10.1002/cjoc.201200448

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A facile and efficient approach to the synthesis of secondary thioamides from ketoximes via Beckmann rearrangement has been established, using phosphorus pentasulfide as a dehydrating and thiating agent. It is also efficient for the preparation of primary thiobenzamide from benzaldoxime. This approach features simple-operation, easy-control and good to excellent yields.

引用

页码：1687 / 1689

页数：3

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