Fine-needle-aspiration cytology of a proximal type epithelioid sarcoma: A case report

被引:11
作者
Pendse, Avani A. [1 ]
Dodd, Leslie G. [1 ]
机构
[1] Univ N Carolina, Dept Pathol, Anat & Clin Pathol, Chapel Hill, NC 27599 USA
关键词
proximal epithelioid sarcoma; epithelioid sarcoma; fine-needle aspiration; INI1; IMMUNOHISTOCHEMICAL ANALYSIS; FEATURES; TUMORS; DIAGNOSIS; GENE;
D O I
10.1002/dc.23294
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Epithelioid sarcoma is a rare mesenchymal neoplasm, with an as yet unidentified cell of origin. Two subtypes of epithelioid sarcoma, distal/classic and proximal/large cell type, are recognized in the literature; with the proximal-type having a lower incidence amongst the two. Here, we present a case of proximal-type epithelioid sarcoma in a previously healthy young man. Fine-needle-aspiration of a large axillary mass was performed for diagnosis. The cytologic findings included a dispersed population of large epithelioid to polyhedral cells with abundant cytoplasm. Immunohistochemical staining showed coexpression of keratin and vimentin, as well as loss of INI1 staining, consistent with an epithelioid sarcoma, proximal subtype. Diagn. Cytopathol. 2015;43:859-862. (c) 2015 Wiley Periodicals, Inc.
引用
收藏
页码:859 / 862
页数:4
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