Blepharospasm and Meige's Syndrome treatment with Botulinum Toxin. Experience and follow-up in 18 cases

Treatment with botulinum toxin (BT) is a good therapeutic alternative for patients with blepharospasm and Meige's syndrome. We report follow up results of 18 patients with blepharospasm and Meige's syndrome treated with botulinum toxin, to asses therapy response. 67 injection sessions were performed with a mean dose of 40.2 +/- 26.5 UI. The duration of effect was 120 50 days and the global assessment of the results on a scale from 0 to 4 (0 no results to 4 very good results) was an average of 3.1 +/- 0.72. We can say that botulinum toxin therapy was good or very good in 14 (77.7%) patients with blepharospasm and Meige's Syndrome. Only 3 cases (16.6%) had significative complications, reversible in all cases.