Osteoporosis in the European Union: a compendium of country-specific reports

被引:515
作者
Svedbom, A. [1 ]
Hernlund, E. [1 ]
Ivergard, M. [1 ]
Compston, J. [2 ]
Cooper, C. [3 ,4 ]
Stenmark, J. [5 ]
McCloskey, E. V. [6 ,7 ]
Jonsson, B. [8 ]
Kanis, J. A. [7 ,9 ]
机构
[1] OptumInsight, Stockholm, Sweden
[2] Univ Cambridge, Addenbrookes Hosp, Dept Med, Cambridge CB2 2QQ, England
[3] Univ Southampton, MRC Lifecourse Epidemiol Unit, Southampton, Hants, England
[4] Univ Oxford, Inst Musculoskeletal Sci, NIHR Musculoskeletal Biomed Res Unit, Oxford, England
[5] Int Osteoporosis Fdn, Nyon, Switzerland
[6] Northern Gen Hosp, Acad Unit Bone Metab, Sheffield S5 7AU, S Yorkshire, England
[7] Univ Sheffield, WHO Collaborating Ctr Metab Bone Dis, Sheffield S10 2RX, S Yorkshire, England
[8] Stockholm Sch Econ, S-11383 Stockholm, Sweden
[9] Univ Sheffield, Sch Med, WHO Collaborating Ctr Metab Bone Dis, Beech Hill Rd, Sheffield S10 2RX, S Yorkshire, England
基金
英国医学研究理事会;
关键词
Epidemiology; Fracture; Economic burden; European Union; Treatment; Health Technology Assessment;
D O I
10.1007/s11657-013-0137-0
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This report describes epidemiology, burden, and treatment of osteoporosis in each of the 27 countries of the European Union (EU27). Introduction In 2010, 22 million women and 5.5 million men were estimated to have osteoporosis in the EU; and 3.5 million new fragility fractures were sustained, comprising 620,000 hip fractures, 520,000 vertebral fractures, 560,000 forearm fractures and 1,800,000 other fractures. The economic burden of incident and prior fragility fractures was estimated at (sic)37 billion. Previous and incident fractures also accounted for 1,180,000 quality-adjusted life years lost during 2010. The costs are expected to increase by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining. The aim of this report was to characterize the burden of osteoporosis in each of the EU27 countries in 2010 and beyond. Methods The data on fracture incidence and costs of fractures in the EU27 were taken from a concurrent publication in this journal (Osteoporosis in the European Union: Medical Management, Epidemiology and Economic Burden) and country specific information extracted. Results The clinical and economic burden of osteoporotic fractures in 2010 is given for each of the 27 countries of the EU. The costs are expected to increase on average by 25 % in 2025. The majority of individuals who have sustained an osteoporosis-related fracture or who are at high risk of fracture are untreated and the number of patients on treatment is declining. Conclusions In spite of the high cost of osteoporosis, a substantial treatment gap and projected increase of the economic burden driven by aging populations, the use of pharmacological prevention of osteoporosis has decreased in recent years, suggesting that a change in healthcare policy concerning the disease is warranted.
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