Recent developments in enzymatic chlorination

被引：28
作者：
Murphy, CD [1 ]
机构：
[1] Natl Univ Ireland Univ Coll Dublin, Ctr Synth & Chem Biol, UCD Sch Biomol & Biomed Sci, Dublin 4, Ireland
来源：
NATURAL PRODUCT REPORTS | 2006年 / 23卷 / 02期
关键词：
D O I：
10.1039/b516588c
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
While the existence of chlorinated natural products has been known for over 100 years, our understanding of the enzymology of biological chlorination reactions has been limited to chloroperoxidases, which are now known not to play a significant role in chlorometabolite biosynthesis. The discoveries of new classes of halogenases, described in this Highlight, have shed new light on the mechanisms of enzymatic chlorination of aromatic and aliphatic compounds.
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收藏
页码：147 / 152
页数：6
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