Unilateral Hypertrophic Osteoarthropathy in a Patient With a Vascular Graft Infection

被引:5
作者
Ahrenstorf, Gerrit [1 ]
Rihl, Markus [2 ]
Pichlmaier, Maximilian A. [3 ]
Rosenthal, Herbert [4 ]
Witte, Torsten [1 ]
Schmidt, Reinhold E. [1 ]
机构
[1] Hannover Med Sch, Clin Immunol & Rheumatol, D-30625 Hannover, Germany
[2] Hannover Med Sch, Clin Rehabil Med, D-30625 Hannover, Germany
[3] Hannover Med Sch, Clin Heart Thorac Transplantat & Vasc Surg, D-30625 Hannover, Germany
[4] Hannover Med Sch, Inst Radiol, D-30625 Hannover, Germany
关键词
hypertrophic osteoarthropathy; digital clubbing; vascular graft infection; PROSTHESIS;
D O I
10.1097/RHU.0b013e3182614d08
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report a patient who presented with high fever; a unilateral, palpable tender swelling along the right shin; and effusions in knee and ankle joints leading to the diagnosis of hypertrophic osteoarthropathy (HOA). The diagnostic workup revealed an infected vascular graft that had been implanted 2 years before because of a ruptured infrarenal aortic aneurysm as the cause of HOA. The patient was treated successfully with antibiotics and surgically replacing the infected graft. Hypertrophic osteoarthritis is a clinical entity characterized by digital clubbing, periostitis, and synovial effusions. Primary and secondary forms have been described. Secondary HOA develops as a consequence of various diseases, mainly intrathoracic malignancies. Vascular graft infection, as reported here, is a rare cause of HOA. This case underlines the typical clinical features of HOA and the importance of a prompt and comprehensive diagnostic workup in cases of HOA. Our aim is to sharpen the awareness of its multiple underlying causes. Unilateral HOA is a rare but strong and important sign of infection of vascular prosthesis.
引用
收藏
页码:307 / 309
页数:3
相关论文
共 14 条
[11]  
MARTINEZLAVIN M, 2007, RHEUMATOLOGY
[12]  
Olán F, 2004, J RHEUMATOL, V31, P614
[13]  
Silveira LH, 2007, CLIN EXP RHEUMATOL, V43, P1857
[14]   Mutations in 15-hydroxyprostaglandin dehydrogenase cause primary hypertrophic osteoarthropathy [J].
Uppal, Sandeep ;
Diggle, Christine P. ;
Carr, Ian M. ;
Fishwick, Colin W. G. ;
Ahmed, Mushtaq ;
Ibrahim, Gamal H. ;
Helliwell, Philip S. ;
Latos-Bielenska, Anna ;
Phillips, Simon E. V. ;
Markham, Alexander F. ;
Bennett, Christopher P. ;
Bonthron, David T. .
NATURE GENETICS, 2008, 40 (06) :789-793