[1] Univ Munich, Friedrich Baur Inst, Dept Neurol, D-80336 Munich, Germany
[2] Santhera Pharmaceut, CH-4410 Liestal, Switzerland
[3] Newcastle Upon Tyne Fdn Hosp NHS Fdn Trust, Dept Neurol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
[4] Newcastle Upon Tyne Fdn Hosp NHS Fdn Trust, Dept Ophthalmol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
[5] Newcastle Univ, Inst Med Genet, Newcastle Upon Tyne NE1 3BZ, Tyne & Wear, England
[6] Univ Munich, Dept Ophthalmol, D-80336 Munich, Germany
[7] CHUM, Dept Ophthalmol, Montreal, PQ H2L 4M1, Canada