Promoter discovery: identification of novel cell type-specific and highly active synthetic promoters for gene therapy vectors

被引：0
作者：
Bilski, M. [1 ]
Dudchenko, O. [1 ]
Silva, C. [1 ]
Singh, P. [1 ]
Broadhurst, B. [1 ]
Du Toit, Y. [1 ]
Parker-Manuel, R. [1 ]
Cawood, R. [1 ]
Brighty, D. W. [1 ]
机构：
[1] OXGENE, Oxford, England
来源：
HUMAN GENE THERAPY | 2022年 / 33卷 / 23-24期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
P102
引用
收藏
页码：A51 / A51
页数：1
相关论文
共 50 条
  • [21] Methylation of the mouse DIx5 and osx gene promoters regulates cell type-specific gene expression
    Lee, Ji Yun
    Lee, Yu Mi
    Kim, Mi Jin
    Choi, Je Yong
    Park, Eui Kyun
    Kim, Shin Yoon
    Lee, Sam Poong
    Yang, Jae Sup
    Kim, Dong Sun
    [J]. MOLECULES AND CELLS, 2006, 22 (02) : 182 - 188
  • [22] In vivo cell type-specific gene delivery with retroviral vectors that display single chain antibodies
    Jiang, A
    Dornburg, R
    [J]. GENE THERAPY, 1999, 6 (12) : 1982 - 1987
  • [23] Identification of Synuclein-γ (SNGC) Promoter as a Novel Retinal Ganglion Cell-Specific Promoter for Neuroprotection Gene Therapy
    Wang, Qizhao
    Wang, Haoliang
    Kreymerman, Alexander
    Siew, Leonard
    Liu, Liang
    Hu, Yang
    [J]. MOLECULAR THERAPY, 2018, 26 (05) : 261 - 262
  • [24] In vivo cell type-specific gene delivery with retroviral vectors that display single chain antibodies
    A Jiang
    R Dornburg
    R Dornburg
    [J]. Gene Therapy, 1999, 6 : 1982 - 1987
  • [25] Construction of Viral Vectors for Cell Type-specific CRISPR Gene Editing in the Adult Mouse Brain
    Yamaguchi, Hiroshi
    de Lecea, Luis
    [J]. BIO-PROTOCOL, 2019, 9 (16):
  • [26] Novel and Highly Potent Selective Synthetic Promoters for Muscle-Directed Gene Therapy Applications
    Yanez-Cuna, J. Omar
    Guerrini, Ileana
    Di Santo, Rachael
    Kippen, Nicolle
    Scialpi, Flavia
    Katsoupi, Polyxeni
    Rajan, Rinku
    Iglesias-Gonzalez, Juan Manuel
    Roberts, Michael Leslie
    [J]. MOLECULAR THERAPY, 2021, 29 (04) : 296 - 297
  • [27] Somatic Transgenesis Modeling in the Brain Using Different Promoters to Target Cell Type-Specific Gene Expression
    Modrow, S.
    Cruz, P. E.
    Ceballos-Diaz, C.
    Rosario, A. M.
    Golde, T. E.
    Chakrabarty, P.
    [J]. CELL TRANSPLANTATION, 2018, 27 (04) : 705 - 706
  • [28] Tissue and Cell Type-Specific rAAV Gene Therapy Reveals a Novel Therapeutic Cell Target and Biomarker for Canavan Disease
    Li, Danning
    Gessler, Dominic J.
    Su, Qin
    Matalon, Reuben
    Gao, Guangping
    [J]. MOLECULAR THERAPY, 2017, 25 (05) : 310 - 310
  • [29] CELL TYPE-SPECIFIC EXPRESSION OF THE HUMAN TRANSFERRIN GENE - ROLE OF PROMOTER, NEGATIVE, AND ENHANCER ELEMENTS
    SCHAEFFER, E
    BOISSIER, F
    PY, MC
    COHEN, GN
    ZAKIN, MM
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1989, 264 (13) : 7153 - 7160
  • [30] Cell type-specific regulation of CREB gene expression: Mutational analysis of CREB promoter activity
    Coven, E
    Ni, Y
    Widnell, KL
    Chen, J
    Walker, WH
    Habener, JF
    Nestler, EJ
    [J]. JOURNAL OF NEUROCHEMISTRY, 1998, 71 (05) : 1865 - 1874
12345