Peginterferon Lambda, a New Potential Therapeutic Option for the Treatment of Chronic Hepatitis B: A Phase 2B Comparison with Peginterferon Alfa in Patients with HBeAg-Positive Disease

被引：0
|
作者：
Chan, Henry Lik-Yuen [1 ]
Ahn, Sang Hoon [2 ]
Chang, Ting-Tsung [3 ]
Peng, Cheng-Yuan [4 ]
Wong, David K. [5 ]
Coffin, Carla S. [6 ]
Lim, Seng Gee [7 ]
Chen, Pei-Jer [8 ]
Janssen, Harry L. [9 ]
Marcellin, Patrick [10 ]
Serfaty, Lawrence [11 ]
Zeuzem, Stefan [12 ]
Hu, Wenhua [13 ]
Critelli, Linda [13 ]
Lopez-Talavera, Juan Carlos [13 ]
Cooney, Elizabeth L. [13 ]
机构：
[1] Chinese Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China
[2] Yonsei Univ, Severance Hosp, Seoul 120749, South Korea
[3] Natl Cheng Kung Univ Hosp, Tainan 70428, Taiwan
[4] China Med Univ Hosp, Taichung, Taiwan
[5] Toronto Western Hosp, Univ Hlth Network, Toronto, ON M5T 2S8, Canada
[6] Univ Calgary, Div Gastroenterol & Hepatol, Liver Unit, Calgary, AB, Canada
[7] Natl Univ Singapore Hosp, Singapore 117548, Singapore
[8] Natl Taiwan Univ Hosp, Taipei, Taiwan
[9] Erasmus MC, Rotterdam, Netherlands
[10] Hop Beaujon, Clichy, France
[11] Hop St Antoine, F-75571 Paris, France
[12] Goethe Univ Frankfurt, D-60054 Frankfurt, Germany
[13] Bristol Myers Squibb Res & Dev, Wallingford, CT USA
来源：
HEPATOLOGY | 2012年 / 56卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
LB14
引用
收藏
页码：1525 / 1526
页数：2
相关论文
共 50 条
  • [41] STRONGER HBV DNA SUPPRESSION IN PATIENTS WITH HBEAG-POSITIVE CHRONIC HEPATITIS B ACHIEVING HBEAG CLEARANCE DURING PEGINTERFERON ALFA-2B THERAPY COMPARED WITH PLACEBO
    Hansen, Bettina E.
    Rijckborst, Vincent
    ter Borg, Martijn J.
    Janssen, Harry L.
    HEPATOLOGY, 2010, 52 (04) : 563A - 563A
  • [42] Significance of T-Cell Subsets for Clinical Response to Peginterferon Alfa-2a Therapy in HBeAg-Positive Chronic Hepatitis B Patients
    Zhu, Li
    Li, Jin
    Xu, Junchi
    Chen, Fan
    Wu, Xunxun
    Zhu, Chuanwu
    INTERNATIONAL JOURNAL OF GENERAL MEDICINE, 2022, 15 : 4441 - 4451
  • [43] Sustained response to peginterferon alfa-2a (40 kD) with or without lamivudine in Asian patients with HBeAg-positive and HBeAg-negative chronic hepatitis B
    Piratvisuth, Teerha
    Lau, George
    Chao, You-Chen
    Jin, Rui
    Chutaputti, Anuchit
    Zhang, Q. -B.
    Tanwandee, Tawesak
    Button, Peter
    Popescu, Matei
    HEPATOLOGY INTERNATIONAL, 2008, 2 (01) : 102 - 110
  • [44] Sustained response to peginterferon alfa-2a (40 kD) with or without lamivudine in Asian patients with HBeAg-positive and HBeAg-negative chronic hepatitis B
    Teerha Piratvisuth
    George Lau
    You-Chen Chao
    Rui Jin
    Anuchit Chutaputti
    Q.-B. Zhang
    Tawesak Tanwandee
    Peter Button
    Matei Popescu
    Hepatology International, 2008, 2 : 102 - 110
  • [45] EFFICACY OF PEGINTERFERON ALFA-2A OR ALFA-2B IN TREATMENT OF HBEAG NEGATIVE CHRONIC HEPATITIS B INFECTION
    Karabay, Oguz
    Tuna, Nazan
    Esen, Saban
    HEPATOLOGY, 2011, 54 : 1061A - 1061A
  • [46] Quantitation of large, middle and small hepatitis B surface proteins in HBeAg-positive patients treated with peginterferon alfa-2a
    Rinker, Franziska
    Bremer, Corinna M.
    Schroeder, Kathrin
    Wiegand, Steffen B.
    Bremer, Birgit
    Manns, Michael P.
    Kraft, Anke R.
    Wedemeyer, Heiner
    Yang, Lei
    Pavlovic, Vedran
    Wat, Cynthia
    Gerlich, Wolfram H.
    Glebe, Dieter
    Cornberg, Markus
    LIVER INTERNATIONAL, 2020, 40 (02) : 324 - 332
  • [47] Improvement of response prediction applying a dynamic modification during treatment with peginterferon in HBeAg-positive chronic hepatitis B patients
    Hansen, Bettina E.
    Chan, Henry Lik-Yuen
    Sonneveld, Milan J.
    Wong, Vincent W.
    Piratvisuth, Teerha
    Janssen, Harry L.
    HEPATOLOGY, 2012, 56 : 377A - 377A
  • [48] QUANTITATIVE HEPATITIS B CORE ANTIBODY LEVEL IS A NEW BASELINE PREDICTOR FOR TREATMENT RESPONSE IN HBeAg-POSITIVE CHRONIC HEPATITIS B PATIENTS RECEIVING PEGINTERFERON THERAPY
    Wang, G. -Q.
    Hou, F. -Q.
    Song, L. -W.
    Xia, N. -S.
    Yuan, Q.
    Fang, L. -L.
    Ge, S. -X.
    Zhang, J.
    Sun, L.
    Sheng, J. -F.
    Xie, D. -Y.
    Shang, J.
    Wu, S. -H.
    Sun, Y. -T.
    Wei, S. -F.
    JOURNAL OF HEPATOLOGY, 2014, 60 (01) : S439 - S439
  • [49] Polymorphisms Near IL28B and Serologic Response to Peginterferon in HBeAg-Positive Patients With Chronic Hepatitis B
    Sonneveld, Milan J.
    Wong, Vincent W-S.
    Woltman, Andrea M.
    Wong, Grace L. H.
    Cakaloglu, Yilmaz
    Zeuzem, Stefan
    Buster, Erik H. C. J.
    Uitterlinden, Andre G.
    Hansen, Bettina E.
    Chan, Henry L. Y.
    Janssen, Harry L. A.
    GASTROENTEROLOGY, 2012, 142 (03) : 513 - U165
  • [50] New treatment strategy: switching from long-term entecavir to peginterferon alfa-2a induces HBeAg seroconversion/HBsAg clearance in patients with HBeAg-positive chronic hepatitis B
    Ning, Qin
    Han, Meifang
    Sun, Yongtao
    Jiang, Jia-ji
    Tan, Deming
    Hou, Jinlin
    Tang, Hong
    Sheng, Jifang
    Zhao, Mianzhi
    HEPATOLOGY, 2012, 56 : 300A - 301A
12345