Peginterferon Lambda, a New Potential Therapeutic Option for the Treatment of Chronic Hepatitis B: A Phase 2B Comparison with Peginterferon Alfa in Patients with HBeAg-Positive Disease

被引：0

作者：

Chan, Henry Lik-Yuen ^{[1
]}

Ahn, Sang Hoon ^{[2
]}

Chang, Ting-Tsung ^{[3
]}

Peng, Cheng-Yuan ^{[4
]}

Wong, David K. ^{[5
]}

Coffin, Carla S. ^{[6
]}

Lim, Seng Gee ^{[7
]}

Chen, Pei-Jer ^{[8
]}

Janssen, Harry L. ^{[9
]}

Marcellin, Patrick ^{[10
]}

Serfaty, Lawrence ^{[11
]}

Zeuzem, Stefan ^{[12
]}

Hu, Wenhua ^{[13
]}

Critelli, Linda ^{[13
]}

Lopez-Talavera, Juan Carlos ^{[13
]}

Cooney, Elizabeth L. ^{[13
]}

机构：

[1] Chinese Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China

[2] Yonsei Univ, Severance Hosp, Seoul 120749, South Korea

[3] Natl Cheng Kung Univ Hosp, Tainan 70428, Taiwan

[4] China Med Univ Hosp, Taichung, Taiwan

[5] Toronto Western Hosp, Univ Hlth Network, Toronto, ON M5T 2S8, Canada

[6] Univ Calgary, Div Gastroenterol & Hepatol, Liver Unit, Calgary, AB, Canada

[7] Natl Univ Singapore Hosp, Singapore 117548, Singapore

[8] Natl Taiwan Univ Hosp, Taipei, Taiwan

[9] Erasmus MC, Rotterdam, Netherlands

[10] Hop Beaujon, Clichy, France

[11] Hop St Antoine, F-75571 Paris, France

[12] Goethe Univ Frankfurt, D-60054 Frankfurt, Germany

[13] Bristol Myers Squibb Res & Dev, Wallingford, CT USA

来源：

HEPATOLOGY | 2012年 / 56卷 / 06期

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

LB14

引用

页码：1525 / 1526

页数：2

共 50 条

[1] PEGINTERFERON LAMBDA FOR THE TREATMENT OF CHRONIC HEPATITIS B (CHB): A PHASE 2B COMPARISON WITH PEGINTERFERON ALFA IN PATIENTS WITH HBeAg-POSITIVE DISEASE
Chan, H. L.
Ahn, S. H.
Chang, T. -T.
Peng, C. -Y.
Wong, D.
Coffin, C. S.
Lim, S. G.
Chen, P. -J.
Janssen, H. L.
Marcellin, P.
Serfaty, L.
Zeuzem, S.
Cohen, D.
Critelli, L.
Xu, D.
Cooney, E.
JOURNAL OF HEPATOLOGY, 2014, 60 (01) : S48 - S48
[2] ALT FLARES DURING TREATMENT WITH PEGINTERFERON LAMBDA OR PEGINTERFERON alfa IN PATIENTS WITH HBeAg-POSITIVE CHRONIC HEPATITIS B INFECTION (CHB)
Chan, H. L.
Ahn, S. H.
Chang, T. -T.
Peng, C. -Y.
Wong, D.
Coffin, C.
Lim, S. G.
Chen, P. -J.
Janssen, H. L.
Marcellin, P.
Serfaty, L.
Zeuzem, S.
Hu, W.
Critelli, L.
Wind-Rotolo, M.
Srinivasan, S.
Lopez-Talavera, J. C.
Cooney, E.
JOURNAL OF HEPATOLOGY, 2013, 58 : S300 - S300
[3] Peginterferon lambda for the treatment of HBeAg-positive chronic hepatitis B: A randomized phase 2b study (LIRA-B)
Chan, Henry L. Y.
Ahn, Sang Hoon
Chang, Ting-Tsung
Peng, Cheng-Yuan
Wong, David
Coffin, Carla S.
Lim, Seng Gee
Chen, Pei-Jer
Janssen, Harry L. A.
Marcellin, Patrick
Serfaty, Lawrence
Zeuzem, Stefan
Cohen, David
Critelli, Linda
Xu, Dong
Wind-Rotolo, Megan
Cooney, Elizabeth
JOURNAL OF HEPATOLOGY, 2016, 64 (05) : 1011 - 1019
[4] Peginterferon alfa-2b in the treatment of Chinese patients with HBeAg-positive chronic hepatitis B: A randomized trial
Cheng, Jun
Wang, Yuming
Hou, Jinlin
Luo, Duande
Xie, Qing
Ning, Qin
Ren, Hong
Ding, Huiguo
Sheng, Jifang
Wei, Lai
Chen, Shijun
Fan, Xiaoling
Huang, Wenxiang
Pan, Chen
Gao, Zhiliang
Zhang, Jiming
Zhou, Boping
Chen, Guofeng
Wan, Mobin
Tang, Hong
Wang, Guiqiang
Yang, Yuxiu
Mohamed, Rosmawati
Guan, Richard
Lee, Tzong-Hsi
Chang, Wen-Hsiung
Huang Zhenfei
Ye, Zhang
Xu, Daozhen
JOURNAL OF CLINICAL VIROLOGY, 2014, 61 (04) : 509 - 516
[5] Peginterferon alfa-2a, lamivudine, and the combination for HBeAg-positive chronic hepatitis B
Lau, GKK
Piratvisuth, T
Luo, KX
Marcellin, P
Thongsawat, S
Cooksley, G
Gane, E
Fried, MW
Chow, WC
Paik, SW
Chang, WY
Berg, T
Flisiak, R
McCloud, P
Pluck, N
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (26): : 2682 - 2695
[6] Treatment of HBeAg-positive hepatitis B with peginterferon and lamivudine
Song, K
Rajvanshi, P
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (15): : 1630 - 1630
[7] Efficacy and safety of peginterferon alfa-2a in Chinese patients with HBeAg-positive chronic hepatitis B
Xu, D. -Z.
Xie, Y.
Wei, L.
Chen, X. Y.
Wan, M. -B.
Wang, Y. -M.
Wang, L.
Wei, J.
Gan, J. -H.
Tian, D. -Y.
Zhang, S. -L.
JOURNAL OF HEPATOLOGY, 2008, 48 : S266 - S266
[8] A baseline tool for predicting response to peginterferon alfa-2a in HBeAg-positive patients with chronic hepatitis B
Chan, H. L. Y.
Messinger, D.
Papatheodoridis, G. V.
Cornberg, M.
Xie, Q.
Piratvisuth, T.
Ren, H.
Kennedy, P. T.
Thompson, A.
Caputo, A.
Bakalos, G.
Pavlovic, V.
Lampertico, P.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, 2018, 48 (05) : 547 - 555
[9] PREDICTORS OF DEVELOPMENT OF HBEAG-NEGATIVE CHRONIC HEPATITIS B FOLLOWING PEGINTERFERON ALFA-2A THERAPY IN HBEAG-POSITIVE CHRONIC HEPATITIS B
Peng, Cheng-Yuan
Shih, Chao-Jen
Lo, Pei-Shuan
Huang, Chia-Lin
Lai, Hsueh-Chou
Su, Wen-Pang
Chuang, Po-Heng
Kao, Jung-Ta
HEPATOLOGY, 2011, 54 : 1027A - 1028A
[10] HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B
Fried, Michael W.
Piratvisuth, Teerha
Lau, George K. K.
Marcellin, Patrick
Chow, Wan-Cheng
Cooksley, Graham
Luo, Kang-Xian
Paik, Seung Woon
Liaw, Yun-Fan
Button, Peter
Popescu, Matei
HEPATOLOGY, 2008, 47 (02) : 428 - 434

← 1 2 3 4 5 →