Antifungal principles from Piper fulvescens

被引：29
作者：
Freixa, B
Vila, R
Ferro, EA
Adzet, T
Cañigueral, S
机构：
[1] Univ Barcelona, Fac Farm, Unitat Farmacol & Farmacognosia, E-08028 Barcelona, Spain
[2] Univ Asuncion, Fac Ciencias Quim, Asuncion, Paraguay
来源：
PLANTA MEDICA | 2001年 / 67卷 / 09期
关键词：
D O I：
10.1055/s-2001-18838
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans; identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans, against five fungi strains were determined. Conocarpan showed the widest activity, whereas eupomatenoid 6 was the most active against dermatophytes.
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收藏
页码：873 / 875
页数：3
相关论文
共 15 条
[1]   NEOLIGNANS, NOR-NEOLIGNANS AND OTHER COMPOUNDS FROM ROOTS OF KRAMERIA-GRAYI [J].
ACHENBACH, H ;
UTZ, W ;
SANCHEZ, H ;
TOUCHE, EMG ;
VERDE, J ;
DOMINGUEZ, XA .
PHYTOCHEMISTRY, 1995, 39 (02) :413-415
[2]   Studies on Krameriaceae .11. Lignans and neolignans from Krameria parvifolia [J].
Achenbach, H ;
Utz, W ;
Lozano, B ;
Touche, EMG ;
Moreno, S .
PHYTOCHEMISTRY, 1996, 43 (05) :1093-1095
[3]   LIGNANS, NEOLIGNANS AND NORNEOLIGNANS FROM KRAMERIA-CYSTISOIDES [J].
ACHENBACH, H ;
GROSS, J ;
DOMINGUEZ, XA ;
CANO, G ;
STAR, JV ;
BRUSSOLO, LD ;
MUNOZ, G ;
SALGADO, F ;
LOPEZ, L .
PHYTOCHEMISTRY, 1987, 26 (04) :1159-1166
[4]   STUDIES ON KRAMERIACEAE .7. LIGNANS FROM KRAMERIA-IXINA [J].
ACHENBACH, H ;
UTZ, W ;
USUBILLAGA, A ;
RODRIGUEZ, HA .
PHYTOCHEMISTRY, 1991, 30 (11) :3753-3757
[5]   CONSTITUENTS OF EUPOMATIA SPECIES .2. ISOLATION AND STRUCTURE DETERMINATION OF FURTHER EUPOMATENOID LIGNANS FROM BARK OF EUPOMATIA-LAURINA [J].
BOWDEN, BF ;
TAYLOR, WC ;
RITCHIE, E .
AUSTRALIAN JOURNAL OF CHEMISTRY, 1972, 25 (12) :2659-&
[6]   Insecticidal neolignans from Piper decurrens [J].
Chauret, DC ;
Bernard, CB ;
Arnason, JT ;
Durst, T ;
Krishnamurty, HG ;
SanchezVindas, P ;
Moreno, N ;
SanRoman, L ;
Poveda, L .
JOURNAL OF NATURAL PRODUCTS, 1996, 59 (02) :152-155
[7]  
Freixa B, 1998, PHYTOTHER RES, V12, P427, DOI 10.1002/(SICI)1099-1573(199809)12:6&lt
[8]  
427::AID-PTR338&gt
[9]  
3.0.CO
[10]  
2-X
12