Erectile dysfunction

被引:55
作者
Burnett, AL [1 ]
机构
[1] Johns Hopkins Univ, Baltimore, MD USA
关键词
penis; impotence; penile erection; phosphodiesterase V;
D O I
10.1016/S0022-5347(05)00309-5
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: An overview of the latest concepts advanced with regard to the epidemiology, pathophysiology, and management of male ED is provided. Materials and Methods: Published literature and current paradigms promoted by consensus bodies in the field with regard to the management of ED were reviewed. Results: ED is a neurovascular phenomenon modulated by hormonal, local biochemical, and biomechanical/structural factors of the penis. Once viewed primarily as a psychological issue, ED is now understood to represent predominantly organic etiologies. It has a significant association with cardiovascular disease and could serve as a harbinger of subsequent cardiovascular events. Goal directed assessment and management implies a focus on patient (and partner) preferences regarding various treatment options. These options range from oral pharmacological agents to surgery and may be pursued. according to a stepwise management approach. Psychosocial interventions also may serve as useful therapeutic adjuncts. Conclusions: ED is a highly manageable disorder in most patients. The patient and his partner have integral roles in the decision making process, since preferences regarding the importance of sexual activity, and the risks and benefits of treatment will vary greatly among individuals.
引用
收藏
页码:S25 / S31
页数:7
相关论文
共 50 条
[21]   The effect of erectile dysfunction on quality of life: Psychometric testing of a new quality of life measure for patients with erectile dysfunction [J].
MacDonagh, R ;
Ewings, P ;
Porter, T .
JOURNAL OF UROLOGY, 2002, 167 (01) :212-217
[22]   Psychological impact of erectile dysfunction: Validation of a new health related quality of life measure for patients with erectile dysfunction [J].
Latini, DM ;
Penson, DF ;
Colwell, HH ;
Lubeck, DP ;
Mehta, SS ;
Henning, JM ;
Lue, TF .
JOURNAL OF UROLOGY, 2002, 168 (05) :2086-2091
[23]   Efficacy and safety of tadalafil for the treatment of erectile dysfunction: Results of integrated analyses [J].
Brock, GB ;
McMahon, CG ;
Chen, KK ;
Costigan, T ;
Shen, W ;
Watkins, V ;
Anglin, G ;
Whitaker, S .
JOURNAL OF UROLOGY, 2002, 168 (04) :1332-1336
[24]   CONGENITAL ABNORMALITY OF CORPORA CAVERNOSA AND ERECTILE DYSFUNCTION - A CASE-REPORT [J].
TELOKEN, C ;
BUSATO, WFS ;
NETO, JFJ ;
HARTMANN, A ;
WINCKLER, J ;
SOUTO, CAV .
JOURNAL OF UROLOGY, 1993, 149 (05) :1135-1136
[25]   The Psychology of Erectile Dysfunction [J].
Allen, Mark S. ;
Wood, Alex M. ;
Sheffield, David .
CURRENT DIRECTIONS IN PSYCHOLOGICAL SCIENCE, 2023, 32 (06) :487-493
[26]   Sildenafil and erectile dysfunction [J].
Fabbri, A ;
Aversa, A ;
Isidori, A .
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 1999, 22 (06) :486-491
[27]   The management of erectile dysfunction [J].
Schellack, N. ;
Schellack, G. .
SA PHARMACEUTICAL JOURNAL, 2013, 80 (10) :24-28
[28]   Diagnosis of erectile dysfunction [J].
Glina, Sidney ;
Cohen, David J. ;
Vieira, Marcelo .
CURRENT OPINION IN PSYCHIATRY, 2014, 27 (06) :394-399
[29]   Psychogenic erectile dysfunction [J].
Bodie, JA ;
Beeman, WW ;
Monga, M .
INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE, 2003, 33 (03) :273-293
[30]   Genetics of Erectile Dysfunction [J].
Lopushnyan, Natalya A. ;
Chitaley, Kanchan .
JOURNAL OF UROLOGY, 2012, 188 (05) :1676-1683