Emerging Treatment Paradigms in Radiation Oncology

被引：31
作者：
Le, Quynh-Thu [1 ]
Shirato, Hiroki [2 ]
Giaccia, Amato J. [1 ]
Koong, Albert C. [1 ]
机构：
[1] Stanford Univ, Dept Radiat Oncol, Stanford, CA 94305 USA
[2] Hokkaido Univ, Global Inst Collaborat Res & Educ, Global Stn Quantum Med Sci & Engn, Sapporo, Hokkaido, Japan
来源：
CLINICAL CANCER RESEARCH | 2015年 / 21卷 / 15期
关键词：
CELL LUNG-CANCER; HUMAN TUMOR-CELLS; RANDOMIZED-TRIAL; WEE1; KINASE; HEPATOCYTE TRANSPLANTATION; STEREOTACTIC RADIOTHERAPY; HIPPOCAMPAL NEUROGENESIS; IONIZING-RADIATION; ANTITUMOR IMMUNITY; PANCREATIC-CANCER;
D O I：
10.1158/1078-0432.CCR-14-1191
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Rapid advancements in radiotherapy and molecularly targeted therapies have resulted in the development of potential paradigm-shifting use of radiotherapy in the treatment of cancer. In this review, we discuss some of the most promising therapeutic approaches in the field of radiation oncology. These strategies include the use of highly targeted stereotactic radiotherapy and particle therapy as well as combining radiotherapy with agents that modulate the DNA damage response, augment the immune response, or protect normal tissues. (C)2015 AACR.
引用
收藏
页码：3393 / 3401
页数：9
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