Nailfold capillaroscopy in systemic sclerosis: Is there any difference between videocapillaroscopy and dermatoscopy?

被引:22
作者
Dogan, Sibel [1 ]
Akdogan, Ali [2 ]
Atakan, Nilgun [1 ]
机构
[1] Hacettepe Univ, Fac Med, Dept Dermatol, TR-06100 Ankara, Turkey
[2] Hacettepe Univ, Fac Med, Div Rheumatol, Dept Internal Dis, TR-06100 Ankara, Turkey
关键词
scleroderma; nailfold; dermatoscopy; videocapillaroscopy; raynaud's phenomenon; CLASSIFICATION; ABNORMALITIES; INVOLVEMENT; DISEASES;
D O I
10.1111/srt.12067
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
BackgroundVasculopathy is known to destroy nailfold capillary pattern (NCP) in systemic sclerosis (SSc). There are several methods for the evaluation of NCP of which the most common are dermatoscopy and videocapillaroscopy (VCAP). No study has been reported in the literature comparing these two techniques for their diagnostic value. ObjectiveTo compare the diagnostic value of dermatoscopy and VCAP which are widely used to determine changes in the NCP in SSc patients. MethodsA total of 382 nailfolds were visualized. NCP was evaluated in 39 SSc patients using dermatoscopy and VCAP. Defined dermatoscopic groups were matched with early, active and late phase NCP groups determined by VCAP for comparisons. ResultsBoth dermatoscopy and VCAP demonstrated distinct NCP of SSc efficiently. According to dermatoscopic NCP, capillary dilatation, giant capillaries and disrupted vascular configuration were able to be visualized. VCAP revealed early phase NCP in N = 8 (20,5%), active phase in N = 18 (46,2%) and late phase NCP in N = 13 (33.3%) of the patients. Statistical evaluation of grouped data resulted a Cohen kappa value (K) = 0,527. Although VCAP was able to facilitate a more detailed evaluation of NCP, there was no difference between dermatoscopy and VCAP for the identification of distinct NCP in SSc. ConclusionWe suggest that dermatoscopy is efficient enough to identify pathognomonic changes in NCP in SSc as well as VCAP and find dermatoscopy as a very easy applicable and convenient method than VCAP although VCAP facilitates a more detailed evaluation of NCP.
引用
收藏
页码:446 / 449
页数:4
相关论文
共 16 条
[1]   Nailfold capillary abnormalities are prevalent in sclerodermoid graft-versus-host disease and readily detected with dermatoscopy [J].
Akay, B. N. ;
Sanli, H. ;
Topcuoglu, P. ;
Arat, M. ;
Akyol, A. .
BRITISH JOURNAL OF DERMATOLOGY, 2010, 162 (05) :1076-1082
[2]   Rapid improvement of nailfold capillaroscopy after intense immunosuppression for systemic sclerosis and mixed connective tissue disease [J].
Aschwanden, M. ;
Daikeler, T. ;
Jaeger, K. A. ;
Thalhammer, C. ;
Gratwohl, A. ;
Matucci-Cerinic, M. ;
Tyndall, A. .
ANNALS OF THE RHEUMATIC DISEASES, 2008, 67 (07) :1057-1059
[3]   The handheld dermatoscope as a nail-fold capillaroscopic instrument [J].
Bergman, R ;
Sharony, L ;
Schapira, D ;
Nahir, MA ;
Balbir-Gurman, A .
ARCHIVES OF DERMATOLOGY, 2003, 139 (08) :1027-1030
[4]   Persistent association of nailfold capillaroscopy changes and skin involvement over thirty-six months with duration of untreated disease in patients with juvenile dermatomyositis [J].
Christen-Zaech, Stephanie ;
Seshadri, Roopa ;
Sundberg, Joyce ;
Paller, Amy S. ;
Pachman, Lauren M. .
ARTHRITIS AND RHEUMATISM, 2008, 58 (02) :571-576
[5]   Cyclosporin A and iloprost treatment of systemic sclerosis: clinical results and interleukin-6 serum changes after 12 months of therapy [J].
Filaci, G ;
Cutolo, M ;
Scudeletti, M ;
Castagneto, C ;
Derchi, L ;
Gianrossi, R ;
Ropolo, F ;
Zentilin, P ;
Sulli, A ;
Murdaca, G ;
Ghio, M ;
Indiveri, F ;
Puppo, F .
RHEUMATOLOGY, 1999, 38 (10) :992-996
[6]   Vascular complications of scleroderma [J].
Guiducci, Serena ;
Giacomelli, Roberto ;
Cerinic, Marco Matucci .
AUTOIMMUNITY REVIEWS, 2007, 6 (08) :520-523
[7]  
Hudson M, 2007, CLIN EXP RHEUMATOL, V25, P754
[8]   The specificity of capillaroscopic pattern in connective autoimmune diseases. A comparison with microvascular changes in diseases of social importance: arterial hypertension and diabetes mellitus [J].
Lambova, Sevdalina Nikolova ;
Mueller-Ladner, Ulf .
MODERN RHEUMATOLOGY, 2009, 19 (06) :600-605
[9]   The role of capillaroscopy in differentiation of primary and secondary Raynaud's phenomenon in rheumatic diseases: a review of the literature and two case reports [J].
Lambova, Sevdalina Nikolova ;
Mueller-Ladner, Ulf .
RHEUMATOLOGY INTERNATIONAL, 2009, 29 (11) :1263-1271
[10]   OFFICE NAIL FOLD CAPILLARY MICROSCOPY USING OPHTHALMOSCOPE [J].
MINKIN, W ;
RABHAN, NB .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1982, 7 (02) :190-193