Novel linear C22-sesterterpenoids from sponge Ircinia formosana

被引：21
作者：
Shen, Ya-Ching
Lo, Kuang-Liang
Lin, Yu-Chi
Khalil, Ashraf Taha
Kuo, Yao-Haur
Shih, Pei-Show
机构：
[1] Natl Sun Yat Sen Univ, Inst Marine Resources, Kaohsiung 80424, Taiwan
[2] Natl Res Inst Chinese Med, Taipei 112, Taiwan
来源：
TETRAHEDRON LETTERS | 2006年 / 47卷 / 24期
关键词：
D O I：
10.1016/j.tetlet.2006.04.004
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Four unprecedented C-22-sesterterpenes, irciformonins A-D (1-4), have been isolated from the marine sponge Ircinia formosana, collected off the coast of eastern Taiwan. The structures of the isolated metabolites were established on the basis of extensive spectral analysis, primarily 1- and 2D-NMR. Compounds 3 and 4 exhibited significant cytotoxicity against human colon (WiDr) tumor cells. (c) 2006 Elsevier Ltd. All rights reserved.
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页码：4007 / 4010
页数：4
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