The Diabetes Shared Care Program and Risks of Cardiovascular Events in Type 2 Diabetes

被引:35
作者
Kornelius, Edy [1 ,2 ]
Chiou, Jeng-Yuan [3 ]
Yang, Yi-Sun [1 ,2 ]
Lu, Ying-Li [1 ,2 ]
Peng, Chiung-Huei [4 ]
Huang, Chien-Ning [1 ,2 ]
机构
[1] Chung Shan Med Univ Hosp, Div Endocrinol & Metab, Dept Internal Med, Taichung, Taiwan
[2] Chung Shan Med Univ, Inst Med, Taichung, Taiwan
[3] Chung Shan Med Univ, Inst Med, Sch Hlth Policy & Management, Taichung, Taiwan
[4] Hungkuang Univ, Div Basic Med Sci, Taichung, Taiwan
关键词
Cardiovascular events; Diabetes Shared Care Program; Mortality; P4P; Taiwan; RANDOMIZED CONTROLLED-TRIAL; MELLITUS; MORTALITY; DISEASE; TAIWAN; HEMOGLOBIN; OUTCOMES; PEOPLE; ADULTS;
D O I
10.1016/j.amjmed.2015.03.025
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
OBJECTIVE: The Diabetes Shared Care Program (DSCP) is an integrated diabetes care model designed to increase the quality of diabetes care in Taiwan. The efficacy of this program is unknown. Therefore, we evaluated whether participating patients had reduced risks of cardiovascular events, including coronary heart disease, stroke, and all-cause mortality. METHODS: All 120,000 diabetes patients' data in this retrospective cohort study were obtained from Taiwan's National Health Insurance Research Database. DSCP participants received integrated care from a physician, diabetes educator, and dietitian. Otherwise, non-DSCP participants visited a physician without instruction from a diabetes educator or dietitian. We followed these patients until the first hospitalizations due to cardiovascular events. The Kaplan-Meier method was used to estimate the survival curves, and the Cox proportional hazards model was applied to determine the risk of cardiovascular events. RESULTS: A total of 4458 participants and 4458 matched controls were enrolled in this study. Mean age of both participants and nonparticipants was 56 years. DSCP participants had significantly lower risks of cardiovascular events (hazard ratio [HR] 0.86; 95% confidence interval [CI], 0.78-0.95), including stroke (HR 0.84; 95% CI, 0.73-0.98) and all-cause mortality (HR 0.78; 95% CI, 0.63-0.95), compared with nonparticipants. Older age, male, history of hypertension, chronic lung disease, and prescription for insulin secretagogues or insulin tended to have higher cardiovascular risks. Nevertheless, the following drugs reduced the cardiovascular risks: biguanides, alpha-glucosidase inhibitors, and thiazolidinediones. CONCLUSIONS: Participation in the DSCP was associated with lower risks of cardiovascular events, stroke, and all-cause mortality. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:977 / +
页数:12
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