The Therapeutic Potential of Neural Stem Cells in Traumatic Brain Injuries

被引：2

作者：

Kabatas, Serdar ^{[1
]}

Cansever, Tufan ^{[1
]}

Civelek, Erdinc ^{[1
]}

Yilmaz, Cem ^{[1
]}

机构：

[1] Baskent Univ, Dept Neurosurg, TR-34662 Istanbul, Turkey

来源：

CURRENT SIGNAL TRANSDUCTION THERAPY | 2011年 / 6卷 / 03期

关键词：

Angiogenesis; functional recovery; neurogenesis; traumatic brain injury; treatment; stem cell; CENTRAL-NERVOUS-SYSTEM; MARROW STROMAL CELLS; ADULT MAMMALIAN FOREBRAIN; HYPOXIC-ISCHEMIC INJURY; PROGENITOR CELLS; SUBVENTRICULAR ZONE; GROWTH-FACTOR; DENTATE GYRUS; IN-VIVO; SUBSTANTIA-NIGRA;

D O I：

10.2174/157436211797483976

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Traumatic brain injury (TBI) is a major cause of mortality and morbidity in the world. Unfortunately, no effective treatments are currently available for TBI. On the other hand, different types of stem cells have shown to selectively target injured brain and improve functional recovery. Moreover, recent data suggest that strategies regarding neurogenesis and angiogenesis following brain injuries may provide promising results. This paper aims to briefly review the current status and potential of using stem cells in the TBI.

引用

页码：327 / 336

页数：10

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