Pleurodesis outcome in malignant pleural mesothelioma

被引：43

作者：

Fysh, Edward Thomas Hamilton ^{[1
,2
]}

Tan, Sze Khen ^{[1
,3
]}

Read, Catherine Ann ^{[1
]}

Lee, Felicity ^{[1
]}

McKenzie, Kate ^{[1
]}

Olsen, Nola ^{[4
]}

Weerasena, Indunil ^{[1
]}

Threlfall, Timothy ^{[5
]}

de Klerk, Nicholas ^{[4
]}

Musk, A. William ^{[1
,4
]}

Lee, Y. C. Gary ^{[1
,2
]}

机构：

[1] Sir Charles Gairdner Hosp, Resp Dept, Perth, WA, Australia

[2] Univ Western Australia, Dept Med, Sch Med & Pharmacol, Ctr Asthma Allergy & Resp Res, Perth, WA 6009, Australia

[3] Khoo Teck Puat Hosp, Dept Gen Med, Singapore, Singapore

[4] Univ Western Australia, Sch Populat Hlth, Perth, WA 6009, Australia

[5] Western Australia Dept Hlth, Western Australian Canc Registry, Mt Claremont, WA, Australia

来源：

THORAX | 2013年 / 68卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1136/thoraxjnl-2012-203043

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Few data exist on the pleurodesis outcome in patients with malignant pleural mesothelioma (MPM). A retrospective review of the Western Australian Mesothelioma Registry over 5 years revealed 390 evaluable patients. Only a subset of patients (42.3%) underwent pleurodesis, surgically (n=78) or by bedside instillation of sclerosants (n=87). Surgical pleurodesis showed no advantages over bedside pleurodesis in efficacy (32% vs 31% failures requiring further drainage, p=0.98), patient survival (p=0.52) or total time spent in hospital from procedure till death (p=0.36). No clinical, biochemical or radiographic parameters tested adequately predict pleurodesis outcome.

引用

页码：594 / 596

页数：3

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