Exercise Therapies for Parkinson's Disease: A Systematic Review and Meta-Analysis

被引：47

作者：

Choi, Hyun-young ^{[1
]}

Cho, Ki-Ho ^{[2
]}

Jin, Chul ^{[1
]}

Lee, JiEun ^{[1
]}

Kim, Tae-Hun ^{[3
]}

Jung, Woo-Sang ^{[2
]}

Moon, Sang-Kwan ^{[2
]}

Ko, Chang-Nam ^{[2
]}

Cho, Seung-Yeon ^{[2
]}

Jeon, Chan-Yong ^{[4
]}

Choi, Tae Young ^{[5
]}

Lee, Myeong Soo ^{[5
]}

Lee, Sang-Ho ^{[6
]}

Chung, Eun Kyoung ^{[7
]}

Kwon, Seungwon ^{[2
]}

机构：

[1] Kyung Hee Univ, Grad Sch, Dept Korean Med Cardiol & Neurol, Seoul 02447, South Korea

[2] Kyung Hee Univ, Dept Cardiol & Neurol, Coll Korean Med, Seoul 02447, South Korea

[3] Kyung Hee Univ, Korean Med Hosp, Korean Med Clin Trial Ctr, Seoul 02447, South Korea

[4] Gachon Univ, Dept Korean Internal Med, Coll Korean Med, Seongnam 13120, South Korea

[5] Korea Inst Oriental Med, Clin Res Div, Daejeon 34054, South Korea

[6] Gangdong Mokhuri Oriental Med Hosp, Dept Internal Med, Seoul 05316, South Korea

[7] Kyung Hee Univ, Div Clin Pharm, Dept Pharm, Coll Pharm, Seoul 02447, South Korea

来源：

PARKINSONS DISEASE | 2020年 / 2020卷

关键词：

RANDOMIZED CONTROLLED-TRIAL; PEOPLE; BALANCE; PILOT; DISABILITY; SYMPTOMS; FALLS; BODY;

D O I：

10.1155/2020/2565320

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Recently, rehabilitative exercise therapies have been described as an important method of overcoming the limitations of the conventional therapies for Parkinson's disease. The present study aimed to evaluate efficacy and safety of exercise therapies for Parkinson's disease. Randomized controlled trials that evaluated exercise therapies in patients with Parkinson's disease until December 2016 were searched for in five electronic databases: PubMed, CENTRAL, EMBASE, OASIS, and CNKI. Eighteen studies (1,144 patients) were included. The overall methodological quality was not high. Patients who underwent exercise therapies exhibited statistically significant improvements in the total UPDRS, UPDRS II and III, Berg Balance Scale, preferred walking speed, and Timed Up and Go Test compared to patients who underwent nonexercise therapies. In comparison to patients who performed regular activity, patients who underwent exercise therapies exhibited statistically significant improvements in the total UPDRS, UPDRS II, and UPDRS III. Exercise therapies were found to be relatively safe. Exercise therapies might promote improvements in the motor symptoms of Parkinson's disease. However, due to the small number of randomized controlled trials and methodological limitations, we are unable to draw concrete conclusions. Therefore, further studies with better designs will be needed.

引用

页数：22

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