Rituximab followed by mycophenolate mofetil in children with IgM nephropathy

被引:0
|
作者
Gu, Jin'ai [1 ]
Xia, Yonghui [1 ]
Mao, Jianhua [1 ]
Fu, Haidong [1 ]
Liu, Ai'min [1 ]
机构
[1] Zhejiang Univ, Sch Med, Dept Nephrol, Childrens Hosp, Hangzhou 310003, Zhejiang, Peoples R China
基金
中国国家自然科学基金;
关键词
IgM nephropathy; Management; Mycophenolate mofetil; Rituximab; NEPHROTIC SYNDROME;
D O I
10.1007/s13312-012-0168-4
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
IgM nephropathy presents with refractory nephrotic syndrome and its treatment is a significant challenge for pediatricians. We present two patients with IgM nephropathy and frequently relapsing nephrotic syndrome treated with rituximab and subsequently mycophenolate mofetil. Both showed complete remission, which 24 to 30 months later, was still maintained. The role of mycophenolate mofetil therapy in maintaining remission after successful treatment of rituximab in IgM nephropathy needs to be examined.
引用
收藏
页码:831 / 833
页数:3
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