Fluorescence-guided surgery with live molecular navigation - a new cutting edge

被引：478

作者：

Nguyen, Quyen T. ^{[1
]}

Tsien, Roger Y. ^{[2
]}

机构：

[1] Univ Calif San Diego, Div Otolaryngol Head & Neck Surg, La Jolla, CA 92093 USA

[2] Univ Calif San Diego, Dept Pharmacol, Howard Hughes Med Inst, La Jolla, CA 92093 USA

来源：

NATURE REVIEWS CANCER | 2013年 / 13卷 / 09期

关键词：

CELL-PENETRATING PEPTIDES; POSITIVE SURGICAL MARGINS; FOLATE RECEPTOR-ALPHA; IN-VIVO FLUORESCENCE; PROTEASE ACTIVITY; RADICAL PROSTATECTOMY; 5-AMINOLEVULINIC ACID; INDOCYANINE GREEN; CONTRAST AGENTS; OVARIAN-CANCER;

D O I：

10.1038/nrc3566

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A glowing new era in cancer surgery may be dawning. Using fluorescently labelled markers, surgical molecular navigation means that tumours and nerves can be displayed in real time intra-operatively in contrasting pseudocolours, which allows more complete tumour resection while preserving important structures. These advances can potentially cause a paradigm shift in cancer surgery, improving patient outcome and decreasing overall health-care costs.

引用

页码：653 / 662

页数：10

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