Fluorescence-guided surgery with live molecular navigation - a new cutting edge

被引：470
作者：
Nguyen, Quyen T. [1 ]
Tsien, Roger Y. [2 ]
机构：
[1] Univ Calif San Diego, Div Otolaryngol Head & Neck Surg, La Jolla, CA 92093 USA
[2] Univ Calif San Diego, Dept Pharmacol, Howard Hughes Med Inst, La Jolla, CA 92093 USA
来源：
NATURE REVIEWS CANCER | 2013年 / 13卷 / 09期
关键词：
CELL-PENETRATING PEPTIDES; POSITIVE SURGICAL MARGINS; FOLATE RECEPTOR-ALPHA; IN-VIVO FLUORESCENCE; PROTEASE ACTIVITY; RADICAL PROSTATECTOMY; 5-AMINOLEVULINIC ACID; INDOCYANINE GREEN; CONTRAST AGENTS; OVARIAN-CANCER;
D O I：
10.1038/nrc3566
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A glowing new era in cancer surgery may be dawning. Using fluorescently labelled markers, surgical molecular navigation means that tumours and nerves can be displayed in real time intra-operatively in contrasting pseudocolours, which allows more complete tumour resection while preserving important structures. These advances can potentially cause a paradigm shift in cancer surgery, improving patient outcome and decreasing overall health-care costs.
引用
收藏
页码：653 / 662
页数：10
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