Whole-genome sequencing reveals potent therapeutic strategy for monomorphic epitheliotropic intestinal T-cell lymphoma

被引:20
作者
Huang, Dachuan [1 ,2 ]
Lim, Jing Quan [1 ,2 ]
Cheah, Daryl Ming Zhe [1 ]
Kahliab, Khalilatul Hanisah Binte Mohd [1 ]
Laurensia, Yurike [1 ]
Pang, Jane Wan Lu [1 ]
Wong, Esther Kam Yin [1 ]
Chia, Burton Kuan Hui [1 ]
Goh, Jasmine [3 ]
Zhang, Xiyun [3 ]
Chan, Jason Yongsheng [4 ]
Chow, Edward Kai-Hua [3 ]
Tan, Soo Yong [5 ]
Lim, Soon Thye [2 ,4 ,6 ]
Ong, Choon Kiat [1 ,2 ,7 ]
机构
[1] Natl Canc Ctr, Div Med Oncol, Lymphoma Genom Translat Res Lab, Singapore, Singapore
[2] Duke NUS Med Sch, Singapore, Singapore
[3] Natl Univ Singapore, Canc Sci Inst Singapore, Singapore, Singapore
[4] Natl Canc Ctr Singapore, Div Med Oncol, 11 Hosp Dr, Singapore 169610, Singapore
[5] Natl Univ Singapore, Yong Loo Lin Sch Med, Singapore, Singapore
[6] SingHlth Duke NUS Blood Canc Ctr, Singapore, Singapore
[7] Genome Inst Singapore, Singapore, Singapore
基金
英国医学研究理事会;
关键词
MULTICENTER;
D O I
10.1182/bloodadvances.2020001782
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:4769 / 4774
页数:6
相关论文
共 26 条
  • [1] Clock-like mutational processes in human somatic cells
    Alexandrov, Ludmil B.
    Jones, Philip H.
    Wedge, David C.
    Sale, Julian E.
    Campbell, Peter J.
    Nik-Zainal, Serena
    Stratton, Michael R.
    [J]. NATURE GENETICS, 2015, 47 (12) : 1402 - +
  • [2] Novel findings from the Asian Lymphoma Study Group: focus on T and NK-cell lymphomas
    Chan, Jason Yongsheng
    Lim, Soon Thye
    [J]. INTERNATIONAL JOURNAL OF HEMATOLOGY, 2018, 107 (04) : 413 - 419
  • [3] Romidepsin for the treatment of relapsed/refractory peripheral T-cell lymphoma: pivotal study update demonstrates durable responses
    Coiffier, Bertrand
    Pro, Barbara
    Prince, H. Miles
    Foss, Francine
    Sokol, Lubomir
    Greenwood, Matthew
    Caballero, Dolores
    Morschhauser, Franck
    Wilhelm, Martin
    Pinter-Brown, Lauren
    Iyer, Swaminathan Padmanabhan
    Shustov, Andrei
    Nielsen, Tina
    Nichols, Jean
    Wolfson, Julie
    Balser, Barbara
    Horwitz, Steven
    [J]. JOURNAL OF HEMATOLOGY & ONCOLOGY, 2014, 7
  • [4] Linking double-stranded DNA breaks to the recombination activating gene complex directs repair to the nonhomologous end-joining pathway
    Cui, Xiaoping
    Meek, Katheryn
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 104 (43) : 17046 - 17051
  • [5] Application of an ex-vivo drug sensitivity platform towards achieving complete remission in a refractory T-cell lymphoma
    de Mel, Sanjay
    Rashid, Masturah B. M.
    Zhang, Xi Yun
    Goh, Jasmine
    Lee, Chun Tsu
    Poon, Li Mei
    Chan, Esther H. L.
    Liu, Xin
    Chng, Wee Joo
    Chee, Yen Lin
    Lee, Joanne
    Yuen, Yi Ching
    Lim, Jing Quan
    Chia, Burton K. H.
    Laurensia, Yurike
    Huang, DaChuan
    Pang, Wan Lu
    Cheah, Daryl Ming Zhe
    Wong, Esther Kam Yin
    Ong, Choon Kiat
    Tang, Tiffany
    Lim, Soon Thye
    Ng, Siok Bian
    Tan, Soo Yong
    Loi, Hoi-Yin
    Tan, Lip Kun
    Chow, Edward K.
    Jeyasekharan, Anand D.
    [J]. BLOOD CANCER JOURNAL, 2020, 10 (01)
  • [6] Recent advances in intestinal lymphomas
    Foukas, Periklis G.
    de Leval, Laurence
    [J]. HISTOPATHOLOGY, 2015, 66 (01) : 112 - 136
  • [7] Identification of a homozygous JAK3 V674A mutation caused by acquired uniparental disomy in a relapsed early T-cell precursor ALL patient
    Kawashima-Goto, Sachiko
    Imamura, Toshihiko
    Seki, Masafumi
    Kato, Motohiro
    Yoshida, Kenichi
    Sugimoto, Atsuya
    Kaneda, Daisuke
    Fujiki, Atsushi
    Miyachi, Mitsuru
    Nakatani, Takuya
    Osone, Shinya
    Ishida, Hiroyuki
    Taki, Tomohiko
    Takita, Junko
    Shiraishi, Yuichi
    Chiba, Kenichi
    Tanaka, Hiroko
    Miyano, Satoru
    Ogawa, Seishi
    Hosoi, Hajime
    [J]. INTERNATIONAL JOURNAL OF HEMATOLOGY, 2015, 101 (04) : 411 - 416
  • [8] Enteropathy-associated T-cell lymphoma-a clinicopathologic and array comparative genomic hybridization study
    Ko, Young Hyeh
    Karnan, Sivasundaram
    Kim, Kyeong Mee
    Park, Cheol Keun
    Kang, Eun Suk
    Kim, Young Ho
    Kang, Won Ki
    Kim, Seok Jin
    Kim, Won Seog
    Lee, Woo Yong
    Chun, Ho Kyung
    Seto, Masao
    [J]. HUMAN PATHOLOGY, 2010, 41 (09) : 1231 - 1237
  • [9] Janus Kinase 3-Activating Mutations Identified in Natural Killer/T-cell Lymphoma
    Koo, Ghee Chong
    Tan, Soo Yong
    Tang, Tiffany
    Poon, Song Ling
    Allen, George E.
    Tan, Leonard
    Chong, Soo Ching
    Ong, Whee Sze
    Tay, Kevin
    Tao, Miriam
    Quek, Richard
    Loong, Susan
    Yeoh, Kheng-Wei
    Yap, Swee Peng
    Lee, Kuo Ann
    Lim, Lay Cheng
    Tan, Daryl
    Goh, Christopher
    Cutcutache, Ioana
    Yu, Willie
    Ng, Cedric Chuan Young
    Rajasegaran, Vikneswari
    Heng, Hong Lee
    Gan, Anna
    Ong, Choon Kiat
    Rozen, Steve
    Tan, Patrick
    Teh, Bin Tean
    Lim, Soon Thye
    [J]. CANCER DISCOVERY, 2012, 2 (07) : 591 - 597
  • [10] Mutalisk: a web-based somatic MUTation AnaLyIS toolKit for genomic, transcriptional and epigenomic signatures
    Lee, Jongkeun
    Lee, Andy Jinseok
    Lee, June-Koo
    Park, Jongkeun
    Kwon, Youngoh
    Park, Seongyeol
    Chun, Hyonho
    Ju, Young Seok
    Hong, Dongwan
    [J]. NUCLEIC ACIDS RESEARCH, 2018, 46 (W1) : W102 - W108