Nutraceuticals and blood pressure control: a European Society of Hypertension position document

被引：50

作者：

Borghi, Claudio ^{[1
]}

Tsioufis, Konstantinos ^{[2
]}

Agabiti-Rosei, Enrico ^{[3
]}

Burnier, Michel ^{[4
]}

Cicero, Arrigo F. G. ^{[1
]}

Clement, Denis ^{[5
]}

Coca, Antonio ^{[6
]}

Desideri, Giovambattista ^{[7
]}

Grassi, Guido ^{[8
]}

Lovic, Dragan ^{[9
]}

Lurbe, Empar ^{[10
]}

Kahan, Thomas ^{[11
]}

Kreutz, Reinhold ^{[12
]}

Jelakovic, Bojan ^{[13
]}

Polonia, Jorge ^{[14
,15
]}

Redon, Josep ^{[16
]}

Van de Borne, Philippe ^{[17
]}

Mancia, Giuseppe ^{[18
]}

机构：

[1] Univ Bologna, Dept Med & Surg Sci, Bologna, Italy

[2] Natl & Kapodistrian Univ Athens, Cardiol Clin 1, Sch Med, Hippokrat Hosp, Athens, Greece

[3] Univ Brescia, Dept Clin & Expt Sci, Brescia, Italy

[4] CHU Vaudois, Dept Med, Serv Nephrol & Hypertens, Lausanne, Switzerland

[5] Ghent Univ Hosp, Ghent, Belgium

[6] Univ Barcelona, Serv Med Interna, Hosp Clin, Unidad Hipertens & Riesgo Vasc, Barcelona, Spain

[7] Univ Aquila, Dept Life Hlth & Environm Sci, Laquila, Italy

[8] Univ Milano Bicocca, Dept Med & Surg, Milan, Italy

[9] Clin Internal Dis Intermed, Dept Cardiol, Hypertens, Nish, Serbia

[10] Univ Valencia, Consorcio Hosp Gen Univ, Dept Pediatr, Valencia, Spain

[11] Karolinska Inst, Dept Clin Sci, Stockholm, Sweden

[12] Charite Univ Med Berlin, Inst Klin Pharmakol & Toxikol, Berlin, Germany

[13] Univ Zagreb, Univ Hosp Ctr Zagreb, Dept Nephrol Hypertens Dialysis & Transplantat, Sch Med, Zagreb, Croatia

[14] Univ Porto, Dept Med, Fac Med, Porto, Portugal

[15] Univ Porto, CINTESIS, Fac Med, Porto, Portugal

[16] Univ Valencia, Med Interna Serv, Hosp Clin Valencia, Catedrat Med, Valencia, Spain

[17] Univ Libre Bruxelles, Hop Erasme, Serv Cardiol, Brussels, Belgium

[18] Univ Milano Bicocca, IRCCS Inst Auxol Italiano, Milan, Italy

来源：

JOURNAL OF HYPERTENSION | 2020年 / 38卷 / 05期

关键词：

blood pressure; consensus; dietary supplements; food; nutraceuticals; IMPROVES ENDOTHELIAL FUNCTION; EXTRACT WS 1442; CARDIOVASCULAR-DISEASE; DOUBLE-BLIND; MAGNESIUM SUPPLEMENTATION; RISK-FACTORS; COFFEE CONSUMPTION; INORGANIC NITRATE; POMEGRANATE JUICE; POTASSIUM INTAKE;

D O I：

10.1097/HJH.0000000000002353

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

High-normal blood pressure (BP) is associated with an increased risk of cardiovascular disease, however the cost- benefit ratio of the use of antihypertensive treatment in these patients is not yet clear. Some dietary components and natural products seems to be able to significantly lower BP without significant side effects. The aim of this position document is to highlight which of these products have the most clinically significant antihypertensive action and wheter they could be suggested to patients with high-normal BP. Among foods, beetroot juice has the most covincing evidence of antihypertensive effect. Antioxidant-rich beverages (teas, coffee) could be considered. Among nutrients, magnesium, potassium and vitamin C supplements could improve BP. Among nonnutrient-nutraceuticals, soy isoflavones could be suggested in perimenopausal women, resveratrol in insulin-resistant patients, melatonin in study participants with night hypertension. In any case, the nutracutical approach has never to substitute the drug treatment, when needed.

引用

页码：799 / 812

页数：14

共 128 条

[1]

Aburto NJ, 2013, BMJ-BRIT MED J, V346, DOI [10.1136/bmj.f1326, 10.1136/bmj.f1378]

[2] Coenzyme Q biosynthesis in health and disease [J].

Acosta, Manuel Jesus ;

Fonseca, Luis Vazquez ;

Desbats, Maria Andrea ;

Cerqua, Cristina ;

Zordan, Roberta ;

Trevisson, Eva ;

Salviati, Leonardo .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 2016, 1857 (08) :1079-1085

[3] Health benefits of dietary fiber [J].

Anderson, James W. ;

Baird, Pat ;

Davis, Richard H., Jr. ;

Ferreri, Stefanie ;

Knudtson, Mary ;

Koraym, Ashraf ;

Waters, Valerie ;

Williams, Christine L. .

NUTRITION REVIEWS, 2009, 67 (04) :188-205

[4] Calcium Intake From Diet and Supplements and the Risk of Coronary Artery Calcification and its Progression Among Older Adults: 10-Year Follow-up of the Multi-Ethnic Study of Atherosclerosis (MESA) [J].

Anderson, John J. B. ;

Kruszka, Bridget ;

Delaney, Joseph A. C. ;

He, Ka ;

Burke, Gregory L. ;

Alonso, Alvaro ;

Bild, Diane E. ;

Budoff, Matthew ;

Michos, Erin D. .

JOURNAL OF THE AMERICAN HEART ASSOCIATION, 2016, 5 (10)

[5] Stakeholder Discussion to Reduce Population-Wide Sodium Intake and Decrease Sodium in the Food Supply A Conference Report From the American Heart Association Sodium Conference 2013 Planning Group [J].

Antman, Elliott M. ;

Appel, Lawrence J. ;

Balentine, Douglas ;

Johnson, Rachel K. ;

Steffen, Lyn M. ;

Miller, Emily Ann ;

Pappas, Antigoni ;

Stitzel, Kimberly F. ;

Vafiadis, Dorothea K. ;

Whitsel, Laurie .

CIRCULATION, 2014, 129 (25) :E660-E679

[6] Gut microbiota in kidney disease and hypertension [J].

Antza, C. ;

Stabouli, S. ;

Kotsis, V. .

PHARMACOLOGICAL RESEARCH, 2018, 130 :198-203

[7]

Asgary S, 2004, DRUG EXP CLIN RES, V30, P221

[8] Projected Effect of Dietary Salt Reductions on Future Cardiovascular Disease [J].

Bibbins-Domingo, Kirsten ;

Chertow, Glenn M. ;

Coxson, Pamela G. ;

Moran, Andrew ;

Lightwood, James M. ;

Pletcher, Mark J. ;

Goldman, Lee .

NEW ENGLAND JOURNAL OF MEDICINE, 2010, 362 (07) :590-599

[9] Daily potassium intake and sodium-to-potassium ratio in the reduction of blood pressure: a meta-analysis of randomized controlled trials [J].

Binia, Aristea ;

Jaeger, Jonathan ;

Hu, Youyou ;

Singh, Anurag ;

Zimmermann, Diane .

JOURNAL OF HYPERTENSION, 2015, 33 (08) :1509-1520

[10] Vitamin C in plasma is inversely related to blood pressure and change in blood pressure during the previous year in young Black and White women [J].

Block, Gladys ;

Jensen, Christopher D. ;

Norkus, Edward P. ;

Hudes, Mark ;

Crawford, Patricia B. .

NUTRITION JOURNAL, 2008, 7 (1)

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