Gut Microbiota Composition and Activity in Relation to Host Metabolic Phenotype and Disease Risk

被引：392

作者：

Holmes, Elaine ^{[1
]}

Li, Jia V. ^{[1
]}

Marchesi, Julian R. ^{[2
]}

Nicholson, Jeremy K. ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Fac Med, Dept Surg & Canc, London SW7 2AZ, England

[2] Cardiff Univ, Sch Biosci, Cardiff CF10 3AT, S Glam, Wales

来源：

CELL METABOLISM | 2012年 / 16卷 / 05期

基金：

英国医学研究理事会;

关键词：

SYMBIONTS; SYSTEM; HEALTH; DIET; RATS;

D O I：

10.1016/j.cmet.2012.10.007

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The symbiotic gut microbiota modulate health and disease of the host through a series of transgenomic metabolic and immune regulatory axes. We explore connections between microbiome composition and function related to individual metabolic phenotypes and consider these interactions as possible targets for developing new personalized therapies and clinical management strategies.

引用

页码：559 / 564

页数：6

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