Donellanic acids A-C: new cyclopropanic oleanane derivatives from Donella ubanguiensis (Sapotaceae)

被引：12

作者：

Djoumessi, Aurelie V. B. ^{[1
]}

Sandjo, Louis P. ^{[1
,2
]}

Liermann, Johannes C. ^{[2
]}

Schollmeyer, Dieter ^{[2
]}

Kuete, Victor ^{[3
]}

Rincheval, Vincent ^{[4
,5
]}

Berhanu, Abegaz M. ^{[6
]}

Yeboah, Samuel O. ^{[7
]}

Wafo, Pascal ^{[8
]}

Ngadjui, Bonaventure T. ^{[1
,9
]}

Opatz, Till ^{[2
]}

机构：

[1] Univ Yaounde I, Dept Organ Chem, Yaounde, Cameroon

[2] Johannes Gutenberg Univ Mainz, Inst Organ Chem, D-55128 Mainz, Germany

[3] Univ Dschang, Dept Biochem, Dschang, Cameroon

[4] Lab Genet & Biol Cellulaire, F-78035 Versailles, France

[5] Univ Versailles St Quentinen En Yvelines, Versailles, France

[6] African Acad Sci, Nairobi 00502, Kenya

[7] Univ Botswana, Dept Chem, Gaborone, Botswana

[8] Univ Yaounde I, Dept Chem, Higher Teachers Training Coll, Yaounde, Cameroon

[9] Univ Yaounde I, Fac Med & Biomed Sci, Dept Pharmaceut Sci & Tradit Pharmacopoeia, Yaounde, Cameroon

来源：

TETRAHEDRON | 2012年 / 68卷 / 24期

关键词：

Donella ubanguiensis; Sapotaceae; Cyclopropanic triterpenoids; Biological activities; ANTIMICROBIAL ACTIVITY; TRITERPENOIDS; GLYCOSIDES; EXTRACTS; LEAVES;

D O I：

10.1016/j.tet.2012.04.027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new cyclopropanic oleanane triterpenoids and ten known compounds were obtained from Donella ubanguiensis using chromatographic methods. The structures were established on the basis of mass spectrometric and NMR data and by comparison with values reported in the literature. The structures of the new compounds were confirmed by X-ray crystallography. A part of the isolated compounds was evaluated for cytotoxic and antimicrobial activities. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：4621 / 4627

页数：7

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