Perioperative Management of Anticoagulation

被引：9
作者：
Guha, Daipayan [1 ]
Macdonald, R. Loch [1 ,2 ]
机构：
[1] Univ Toronto, Toronto Western Hosp, Dept Surg, Div Neurosurg, 399 Bathurst St,West Wing,4th Floor, Toronto, ON M5T 2S8, Canada
[2] St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr Biomed Sci, Div Neurosurg, 30 Bond St, Toronto, ON M5B 1W8, Canada
来源：
NEUROSURGERY CLINICS OF NORTH AMERICA | 2017年 / 28卷 / 02期
关键词：
Subdural hematoma; Anticoagulation; Antiplatelet; Bleeding; Thrombosis; PROTHROMBIN COMPLEX CONCENTRATE; CHRONIC SUBDURAL-HEMATOMA; IMPROVES PLATELET ACTIVITY; FRESH-FROZEN PLASMA; ATRIAL-FIBRILLATION; INTRACRANIAL HEMORRHAGE; TRANEXAMIC ACID; RISK-FACTORS; INDEPENDENT PREDICTORS; ANTIPLATELET THERAPY;
D O I：
10.1016/j.nec.2016.11.011
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Antiplatelet and anticoagulant drugs (antithrombotics) predispose to acute and chronic subdural hematomas. Patients on these drugs are at higher likelihood of presenting with larger hematomas and more severe neurologic deficits. Standard neurosurgical and neurocritical care of subdural hematomas involves reversal of antithrombosis preoperatively, whereas reversing antiplatelet drugs is less clear. This article highlights the spectrum of antithrombotic agents in common use, their mechanisms of action, and strategies for reversal.
引用
收藏
页码：287 / +
页数：10
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