Efficient new approach for the synthesis of N,N-dialkylamino-1,2,4-triazoles

被引：2

作者：

Zhang, Qiang

Peng, Youyi

Welsh, William J.

机构：

[1] Univ Med & Dent New Jersey, Robert Wood Johnson Med Sch, Dept Pharmacol, Piscataway, NJ 08854 USA

[2] Univ Med & Dent New Jersey, Inst Informat, Piscataway, NJ 08854 USA

来源：

HETEROCYCLES | 2006年 / 68卷 / 12期

关键词：

D O I：

10.3987/COM-06-10886

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 3-N,N-dialkylamino-4,5-diaryl-1,2,4-triazoles were synthesized in high yield under mild reaction conditions by coupling functionalized arylmagnesiums with isothiocyanates and cyclization with Viehe's salts. No selective thionation reaction was required for the preparation of carbamoyl derivatives.

引用

页码：2635 / 2645

页数：11

共 31 条

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