Anti-inflammatory constituents from Phyllostachys makinoi Hayata

被引:1
作者
Liaw, Chia-Ching [1 ,2 ]
Lin, Yu-Chi [1 ,3 ]
Wu, Shao-Yu [4 ,5 ]
Kuo, Jenny Chun-Ling [6 ]
Lin, Zhi-Hu [1 ]
Lin, Kai-Wei [1 ]
Hui-Chi, Huang [7 ]
Kuo, Li-Ming Yang [8 ]
Kuo, Yao-Haur [1 ,9 ]
机构
[1] Natl Res Inst Chinese Med, Div Mat Med Dev, Taipei, Taiwan
[2] Natl Chiayi Univ, Dept Biochem Sci & Technol, Chiayi, Taiwan
[3] Natl Sun Yat Sen Univ, Dept Marine Biotechnol & Resources, Kaohsiung, Taiwan
[4] Natl Yang Ming Univ, Dept Life Sci, Taipei, Taiwan
[5] Natl Yang Ming Univ, Inst Genome Sci, Taipei, Taiwan
[6] Chang Gung Mem Hosp, Ctr Tradit Chinese Med, Div Chinese Internal Med, Taoyuan, Taiwan
[7] China Med Univ, Dept Chinese Pharmaceut Sci & Chinese Med Resourc, Taichung, Taiwan
[8] Starsci Biotech Co Ltd, Dept Res & Dev, Taipei, Taiwan
[9] China Med Univ, Coll Chinese Med, Grad Inst Integrated Med, Taichung, Taiwan
关键词
Phyllostachys makinoi; Phyllomakin A; Quiquelignan C; Anti-NO production; BAMBOO SHAVINGS; FLAVONOIDS; GLYCOSIDES;
D O I
10.1080/14786419.2021.1885406
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A novel chromone analogue, phyllomakin A (1), and a new flavonolignan, (-)-quiquelignan C (2), along with 18 phenolic and 2 triterpenoids, were isolated from the leaves of Phyllostachys makinoi Hayata. The structures of 1-22 were elucidated by an application of various spectroscopic analyses (1D & 2D NMR and MS) and compared with reported data. A biological evaluation showed that compound 3 had very potent anti-NO production activity (IC50 = 4.80 mu M), while compounds 2, 6, 11, and 15 showed moderate inhibitory effects (IC50 = 10.19, 13.26, 13.56, and 10.96 mu M, respectively) without affecting cell viability at 20 mu M.
引用
收藏
页码:1425 / 1432
页数:8
相关论文
共 27 条
  • [1] Cardiovascular protective flavonolignans and flavonoids from Calamus quiquesetinervius
    Chang, Chao-Lin
    Wang, Guei-Jane
    Zhang, Li-Jie
    Tsai, Wen-Jen
    Chen, Ru-Yin
    Wu, Yang-Chang
    Kuo, Yao-Haur
    [J]. PHYTOCHEMISTRY, 2010, 71 (2-3) : 271 - 279
  • [2] Quiquelignan A-H, eight new lignoids from the rattan palm Calamus quiquesetinervius and their antiradical, anti-inflammatory and antiplatelet aggregation activities
    Chang, Chao-Lin
    Zhang, Li-Jie
    Chen, Ru-Yin
    Wu, Chin-Chung
    Huang, Hui-Chi
    Roy, Michael C.
    Huang, Jhih-Ping
    Wu, Yang-Chang
    Kuo, Yao-Haur
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 18 (02) : 518 - 525
  • [3] Antiproliferative Lactams and Spiroenone from Adlay Bran in Human Breast Cancer Cell Lines
    Chung, Cheng-Pei
    Hsu, Chih-Ying
    Lin, Jing-Hui
    Kuo, Yueh-Hsiung
    Chiang, Wenchang
    Lin, Yun-Lian
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2011, 59 (04) : 1185 - 1194
  • [4] Tricin derivatives as anti-inflammatory and anti-allergic constituents from the aerial part of Zizania latifolia
    Lee, Seung-Su
    Baek, Yoon-Su
    Eun, Cheong-Su
    Yu, Mi-Hee
    Baek, Nam-In
    Chung, Dae-kyun
    Bang, Myun-Ho
    Yang, Seun-Ah
    [J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2015, 79 (05) : 700 - 706
  • [5] New Flavonolignan Glycosides from the Aerial Parts of Zizania latifolia
    Lee, Seung-Su
    Baek, Nam-In
    Baek, Yoon-Su
    Chung, Dae-Kyun
    Song, Myoung-Chong
    Bang, Myun-Ho
    [J]. MOLECULES, 2015, 20 (04) : 5616 - 5624
  • [6] Identification and Bioactivities of Resveratrol Oligomers and Flavonoids from Carex folliculata Seeds
    Li, Liya
    Henry, Geneive E.
    Seeram, Navindra P.
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (16) : 7282 - 7287
  • [7] Chiral Surfactant-Type Catalyst: Enantioselective Reduction of Long-Chain Aliphatic Ketoesters in Water
    Lin, Zechao
    Li, Jiahong
    Huang, Qingfei
    Huang, Qiuya
    Wang, Qiwei
    Tang, Lei
    Gong, Deying
    Yang, Jun
    Zhu, Jin
    Deng, Jingen
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 2015, 80 (09) : 4419 - 4429
  • [8] Evaluation of Antihypertensive and Antihyperlipidemic Effects of Bamboo Shoot Angiotensin Converting Enzyme Inhibitory Peptide in Vivo
    Liu, Lianliang
    Liu, Lingyi
    Lu, Baiyi
    Xia, Daozong
    Zhang, Ying
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2012, 60 (45) : 11351 - 11358
  • [9] Lu BY, 2010, AFR J BIOTECHNOL, V9, P6430
  • [10] Glutathione-analogous peptidyl phosphorus esters as mechanism-based inhibitors of γ-glutamyl transpeptidase for probing cysteinyl-glycine binding site
    Nakajima, Mado
    Watanabe, Bunta
    Han, Liyou
    Shimizu, Bun-ichi
    Wada, Kei
    Fukuyama, Keiichi
    Suzuki, Hideyuki
    Hiratake, Jun
    [J]. BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 22 (03) : 1176 - 1194