Spindle pole body duplication: a model for centrosome duplication?

被引：100
作者：
Adams, IR
Kilmartin, JV
机构：
[1] Wellcome CRC, Inst Canc & Dev Biol, Cambridge CB2 1QR, England
[2] MRC, Mol Biol Lab, Cambridge CB2 2QH, England
来源：
TRENDS IN CELL BIOLOGY | 2000年 / 10卷 / 08期
关键词：
D O I：
10.1016/S0962-8924(00)01798-0
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The yeast spindle pole body (SPB) is the functional equivalent of the centrosome and forms the two poles of the mitotic spindle. Before mitosis, both SPBs and centrosomes are present as single copies and must be duplicated to form the bipolar spindle. SPB components have been identified using a combination of biochemistry and genetics, and their role during SPB duplication has been analysed using temperature-sensitive mutants. In this article, we describe structural aspects of SPB duplication and their possible relationship to centrosome duplication.
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收藏
页码：329 / 335
页数：7
相关论文
共 58 条
[1]   Localization of core spindle pole body (SPB) components during SPB duplication in Saccharomyces cerevisiae [J].
Adams, IR ;
Kilmartin, JV .
JOURNAL OF CELL BIOLOGY, 1999, 145 (04) :809-823
[2]  
AMOS WB, 1975, J CELL SCI, V19, P203
[3]   FORMATION OF BASAL BODIES (CENTRIOLES) IN RHESUS MONKEY OVIDUCT [J].
ANDERSON, RG ;
BRENNER, RM .
JOURNAL OF CELL BIOLOGY, 1971, 50 (01) :10-&
[4]   DIRECT INTERACTION BETWEEN YEAST SPINDLE POLE BODY COMPONENTS - KAR1P IS REQUIRED FOR CDC31P LOCALIZATION TO THE SPINDLE POLE BODY [J].
BIGGINS, S ;
ROSE, MD .
JOURNAL OF CELL BIOLOGY, 1994, 125 (04) :843-852
[5]   Saccharomyces cerevisiae cells with defective spindle pole body outer plaques accomplish nuclear migration via half-bridge-organized microtubules [J].
Brachat, A ;
Kilmartin, JV ;
Wach, A ;
Philippsen, B .
MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (05) :977-991
[6]   The yeast spindle pole body is assembled around a central crystal of Spc42p [J].
Bullitt, E ;
Rout, MP ;
Kilmartin, JV ;
Akey, CW .
CELL, 1997, 89 (07) :1077-1086
[7]   DUPLICATION OF SPINDLE PLAQUES AND INTEGRATION OF YEAST-CELL CYCLE [J].
BYERS, B ;
GOETSCH, L .
COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1973, 38 :123-131
[8]  
BYERS B, 1981, A BENZON S, V16, P119
[9]   δ-Tubulin and ε-tubulin:: two new human centrosomal tubulins reveal new aspects of centrosome structure and function [J].
Chang, P ;
Stearns, T .
NATURE CELL BIOLOGY, 2000, 2 (01) :30-35
[10]   The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubule assembly [J].
Chen, XYP ;
Yin, HW ;
Huffaker, TC .
JOURNAL OF CELL BIOLOGY, 1998, 141 (05) :1169-1179
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