AIDS-related progressive multifocal leukoencephalopathy

被引：4

作者：

Abrao, Carolina de Oliveira ^{[1
]}

Machado da Silva, Lissa Rodrigues ^{[1
]}

Silva Souza, Luiz Carlos ^{[1
,2
]}

Bisso, Nathalia de Mello ^{[1
]}

Turchi, Marilia Dalva ^{[2
]}

Guilarde, Adriana Oliveira ^{[2
]}

机构：

[1] Hosp Doencas Trop Dr Anuar Auad, Secretaria Estado Saude Goias, Goiania, Go, Brazil

[2] Univ Fed Goias, Inst Patol Trop & Saude Publ, Goiania, Go, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2021年 / 54卷

关键词：

Progressive multifocal leukoencephalopathy; JC polyomavirus encephalopathy; JC virus;

D O I：

10.1590/0037-8682-0252-2020

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV). Methods: We described the profile of laboratory-confirmed PML cases among AIDS patients. Results: A total of 43 HIV patients with clinical conditions compatible with PML were obtained; 5 cases were confirmed by JCV testing. The main clinical finding was mental confusion. Median CD4 count was 54 cells/mm(3). Conclusions: Three of the five confirmed PML cases died; the time between diagnosis and death was 2, 5, and 6 months. It is important to consider JCV infection as a differential diagnosis.

引用

页码：1 / 4

页数：4

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