An interactive graphical user interface for comprehensive analysis of human and swine cardiac monophasic action potential

被引：3
作者：
Shrivastav, Maneesh [1 ,2 ]
Iaizzo, Paul A. [2 ]
机构：
[1] Medtron Neuromodulat, Minneapolis, MN 55432 USA
[2] Univ Minnesota, Visible Heart Lab, Dept Surg & Biomed Engn, Minneapolis, MN USA
来源：
COMPUTERS IN BIOLOGY AND MEDICINE | 2009年 / 39卷 / 12期
关键词：
Monophasic action potential; Cardiac arrhythmia; Computer analysis; MAP; Graphical user interface; Signal processing; MICROCOMPUTER; DECOMPOSITION; PROGRAM;
D O I：
10.1016/j.compbiomed.2009.09.005
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
This research describes a novel monophasic action potential (MAP) annotation algorithm coupled with an interactive graphical user interface (GUI). This algorithm incorporates a number of features to reduce error. Additionally, the GUI has several convenient features to view and manipulate the annotation visually. We analyzed data from swine and human hearts in normal sinus rhythm, during myocardial ischemia, and while eliciting high rates. Validation results indicate correlation > 90% between human and computer measurements. This analysis system has several clinical applications in electrophysiological interventions, pharmacodynamic therapies, ischemia detection, and/or in assessment of the time course of electrical activation. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1105 / 1116
页数：12
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