A comparative study of pediatric onset psoriasis with adult onset psoriasis

被引:222
作者
Raychaudhuri, SP [1 ]
Gross, J [1 ]
机构
[1] Psoriasis Res Inst, Palo Alto, CA 94301 USA
关键词
D O I
10.1046/j.1525-1470.2000.01746.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Psoriasis in childhood is not uncommon. We report data collected from 223 pediatric onset and 484 adult onset psoriasis patients. In the pediatric onset psoriasis patients (POPPs), prevalence of family history was 68.2% compared to 54% in the adult onset psoriasis patients (AOPPs). Also we noticed that exacerbation of psoriasis induced by precipitating factors such as stress (50.4% in POPPs, 42.7% in AOPPs), pharyngitis (27.9% in POPPs, 12.2% in AOPPs), and trauma (49.6% in POPPs and 38.9% in AOPPs) were more frequent in POPPs. Our data show that the frequency of spontaneous remission in POPPs was 35.3% compared to 24.3% in AOPPs. A disfiguring skin disease in childhood may have profound emotional effects. Childhood psoriasis needs special attention. To achieve a prolonged remission it is essential that children with psoriasis and their parents have an understanding of the exogenous and endogenous factors responsible for the increased morbidity of psoriasis.
引用
收藏
页码:174 / 178
页数:5
相关论文
共 17 条
[1]   NERVE GROWTH-FACTOR IS INCREASED IN PSORIATIC SKIN [J].
FANTINI, F ;
MAGNONI, C ;
BRACCILAUDIERO, L ;
PINCELLI, C .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1995, 105 (06) :854-855
[2]  
Farber EM, 1997, CUTIS, V59, P35
[3]   Is psoriasis a neuroimmunologic disease? [J].
Farber, EM ;
Raychaudhuri, SP .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 1999, 38 (01) :12-15
[4]   NATURAL-HISTORY OF PSORIASIS IN 5,600 PATIENTS [J].
FARBER, EM ;
NALL, ML .
DERMATOLOGICA, 1974, 148 (01) :1-18
[5]  
FARBER EM, 1966, CALIF MED, V105, P415
[6]  
HUTTON KP, 1987, CUTIS, V39, P26
[7]   BROWN ADIPOSE-TISSUE - ITS INVIVO IMMUNOLOGY AND INVOLVEMENT IN NEUROIMMUNOMODULATION [J].
JANKOVIC, BD .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES-SERIES, 1987, 496 :3-26
[8]  
LOMEHOLT G, 1963, PSORIASIS PREVALENCE
[9]   CHILDHOOD PSORIASIS - AN EPIDEMIOLOGIC SURVEY OF 112 PATIENTS [J].
NANDA, A ;
KAUR, S ;
KAUR, I ;
KUMAR, B .
PEDIATRIC DERMATOLOGY, 1990, 7 (01) :19-21
[10]   QUANTIFICATION OF CUTANEOUS SENSORY NERVES AND THEIR SUBSTANCE-P CONTENT IN PSORIASIS [J].
NAUKKARINEN, A ;
NICKOLOFF, BJ ;
FARBER, EM .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1989, 92 (01) :126-129