Understanding the mixed alkali effect on the sinterability and in vitro performance of bioactive glasses

被引：20

作者：

Crovace, Murilo C. ^{[1
]}

Soares, Viviane O. ^{[2
]}

Rodrigues, Ana Candida M. ^{[1
]}

Peitl, Oscar ^{[1
]}

Raucci, Larissa M. S. C. ^{[3
]}

de Oliveira, Paulo T. ^{[3
]}

Zanotto, Edgar D. ^{[1
]}

机构：

[1] Univ Fed Sao Carlos, Dept Mat Engn, Vitreous Mat Lab LaMaV, Sao Carlos, SP, Brazil

[2] Univ Estadual Maringa, Dept Sci, Goioere, PR, Brazil

[3] Univ Sao Paulo, Sch Dent Ribeirao Preto, Cell Culture Lab, Ribeirao Preto, SP, Brazil

来源：

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY | 2021年 / 41卷 / 07期

基金：

巴西圣保罗研究基金会;

关键词：

Bioglass; Sintering; Crystallization; Mixed alkali effect; In vitro bioactivity; BONE-MINERAL DENSITY; CONCURRENT CRYSTALLIZATION; TAPE CAST; CERAMIC SCAFFOLDS; ANGIOGENESIS; BIOGLASS(R); VISCOSITY; POTASSIUM; STRONTIUM; PHOSPHATE;

D O I：

10.1016/j.jeurceramsoc.2020.11.020

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Bioglass 45S5 is widely known for its ability to regenerate bone. However, this glass cannot be fully densified by viscous flow due to its very high tendency for crystallization. In this work, we evaluate the sintering and bioactivity of Bioglass 45S5-based compositions in which Na2O is incrementally replaced by K2O. Our sintering tests demonstrated that the densification of Bioglass 45S5 powders can be significantly enhanced due to a decreased crystallization tendency. The composition in which half of the original Na2O content was substituted by K2O exhibits the highest densification rate, evidencing the mixed alkali effect (MAE) in the viscous-flowdriven sintering process. The replacement of Na2O by K2O significantly improved both the densification rate and the in vitro performance. These results are very relevant for this particular glass and also for the design of new bioactive glasses with improved sinterability.

引用

页码：4391 / 4405

页数：15

共 85 条

[11]

Brink M., 1996, PATENT

[12] Effects of surface treatments on Y-TZP phase stability, microstructure and osteoblast cell response [J].

Bruni, Yesica L. ;

Garrido, Liliana B. ;

Albano, Maria P. ;

Teixeira, Lucas Novaes ;

Rosa, Adalberto Luiz ;

de Oliveira, Paulo Tambasco .

CERAMICS INTERNATIONAL, 2015, 41 (10) :14212-14222

[13] Poly(D,L-lactic acid) coated 45S5 Bioglass®-based scaffolds:: Processing and characterization [J].

Chen, Q. Z. ;

Boccaccini, A. R. .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2006, 77A (03) :445-457

[14] Surface functionalization of Bioglass®-derived porous scaffolds [J].

Chen, Qi-Zhi ;

Rezwan, Kurosch ;

Francon, Virginie ;

Armitage, David ;

Nazhat, Showan N. ;

Jones, Francis H. ;

Boccaccini, Aldo R. .

ACTA BIOMATERIALIA, 2007, 3 (04) :551-562

[15] 45S5 Bioglass®-derived glass-ceramic scaffolds for bone tissue engineering [J].

Chen, QZZ ;

Thompson, ID ;

Boccaccini, AR .

BIOMATERIALS, 2006, 27 (11) :2414-2425

[16] KINETIC PROCESSES INVOLVED IN THE SINTERING AND CRYSTALLIZATION OF GLASS POWDERS [J].

CLARK, TJ ;

REED, JS .

JOURNAL OF THE AMERICAN CERAMIC SOCIETY, 1986, 69 (11) :837-846

[17] Strength and toughness of tape cast bioactive glass 45S5 following heat treatment [J].

Clupper, DC ;

Hench, LL ;

Mecholsky, JJ .

JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2004, 24 (10-11) :2929-2934

[18] Crystallization kinetics of tape cast bioactive glass 45S5 [J].

Clupper, DC ;

Hench, LL .

JOURNAL OF NON-CRYSTALLINE SOLIDS, 2003, 318 (1-2) :43-48

[19]

Clupper DC, 2001, J BIOMED MATER RES, V57, P532, DOI 10.1002/1097-4636(20011215)57:4<532::AID-JBM1199>3.0.CO

[20]

2-3

← 1 2 3 4 5 6 7 8 9 →