Performance of the Sofia SARS-CoV-2 Rapid Antigen Test in Symptomatic and Asymptomatic Pediatric Patients

被引：4

作者：

Freeman, Megan Culler ^{[1
]}

Freeman, Tanner J. ^{[2
]}

Iagnemma, Jennifer ^{[3
]}

Rasmussen, Jayne ^{[4
]}

Heidenreich, Kelly ^{[3
]}

Wells, Alan ^{[2
]}

Hoberman, Alejandro ^{[5
]}

Mitchell, Stephanie L. ^{[2
]}

机构：

[1] Univ Pittsburgh, Dept Pediat, Div Infect Dis, Pittsburgh, PA 15260 USA

[2] Univ Pittsburgh, Dept Pathol, Pittsburgh, PA USA

[3] Childrens Community Pediat, Pittsburgh, PA USA

[4] UPMC Childrens Hosp Pittsburgh, Clin Microbiol Lab, Pittsburgh, PA USA

[5] Univ Pittsburgh, Dept Pediat, Pittsburgh, PA 15260 USA

来源：

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2022年 / 11卷 / 09期

关键词：

antigen assay; COVID-19; pediatrics; rapid test; RT-PCR; SARS-CoV-2; METHODOLOGY;

D O I：

10.1093/jpids/piac035

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Quidel Sofia SARS-CoV-2 antigen test has better diagnostic performance for SARS-CoV-2 infection in symptomatic children than in asymptomatic children. The sensitivity and specificity of SARS-CoV-2 antigen tests have not been widely assessed in children. We evaluated children presenting to outpatient care with Quidel Sofia SARS-CoV-2 antigen test (Sofia-Ag-RDT) compared against Cepheid Xpert Xpress SARS-CoV-2/Flu/RSV reverse transcriptase-polymerase chain reaction test from November 2020 to April 2021. Sofia-Ag-RDT had the highest sensitivity in symptomatic (82%; 95% confidence interval, 68%-91%) children.

引用

页码：417 / 421

页数：5

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