Steroid and antibacterial steroidal glycosides from marine green alga Codium iyengarii Borgesen

被引：36

作者：

Ali, MS

Saleem, M

Yamdagni, R

Ali, MA

机构：

[1] Univ Karachi, HEJ Res Inst Chem, Karachi 75270, Pakistan

[2] Univ Calgary, Dept Chem, Calgary, AB T2N 1N4, Canada

[3] Sindh Med Coll, Dept Biochem, Karachi, Pakistan

来源：

NATURAL PRODUCT LETTERS | 2002年 / 16卷 / 06期

关键词：

Codium iyengarii; green alga; Arabian Sea; steroids; steroidal-glycosides; structure elucidation; spectroscopy; bactericidal activity;

D O I：

10.1080/10575630290034249

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The ethyl acetate soluble part of methanolic extract of marine green alga Codium iyengarii collected from Karachi coast of Arabian Sea afforded a new steroid (1, iyengadione) and two new steroidal glycosides [iyengaroside-A (2) and B (3)] along with clerosterol galactoside (4). Their structures were elucidated with the aid of 1D-NMR spectroscopy and reconfirmed through HMBC experiments. The bactericidal activity of 1-4 was also explored and found positive response from iyengaroside-A (2) and clerosterol galactoside (4).

引用

页码：407 / 413

页数：7

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