Mutually induced formation of host-guest complexes between p-sulfonated calix[8]arene and photolabile cholinergic ligands

被引：45
|
作者：
Specht, A
Bernard, P
Goeldner, M
Peng, L
机构：
[1] Univ Louis Pasteur Strasbourg 1, CNRS, UMr 7514, Chim Bioorgan Lab, F-67401 Illkirch Graffenstaden, France
[2] Wuhan Univ, Dept Chem, Wuhan 430072, Peoples R China
[3] AFMB, CNRS, UMR 6098, F-13009 Marseille, France
[4] Univ Louis Pasteur Strasbourg 1, Fac Pharm, Lab Pharmacochim Commun Cellulaire, F-67401 Illkirch Graffenstaden, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2002年 / 41卷 / 24期
关键词：
calixarenes; cholinergic ligands; host-guest systems; inclusion compounds; receptors;
D O I：
10.1002/anie.200290023
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Adaptive systems: The conformationally flexible p-sulfonated calix[8]arene and photolabile cholinergic ligands adapt to each other and select the right conformers to form ditopic binding complexes (see schematic representation), thus mimicking ligand binding in biological receptors or enzymes.
引用
收藏
页码：4706 / 4708
页数：3
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