Effect of ibuprofen on the efficacy of inferior alveolar nerve block in patients with irreversible pulpitis: A meta-analysis

被引：12

作者：

de Geus, Juliana L. ^{[1
,2
,3
]}

Wambier, Leticia M. ^{[4
]}

Boing, Thaynara F. ^{[3
]}

Loguercio, Alessandro D. ^{[1
]}

Reis, Alessandra ^{[1
]}

机构：

[1] Univ Estadual Ponta Grossa, Dept Dent, Ponta Grossa, PR, Brazil

[2] Paulo Picanco Sch Dent, Dept Dent, Fortaleza, Ceara, Brazil

[3] Guairaca Fac, Dept Restorat Dent, Guarapuava, PR, Brazil

[4] Positivo Univ, Dept Pediat Dent, Curitiba, Parana, Brazil

来源：

AUSTRALIAN ENDODONTIC JOURNAL | 2019年 / 45卷 / 02期

关键词：

ibuprofen; inferior alveolar nerve block; irreversible pulpitis; meta-analysis; systematic review; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; PREOPERATIVE ORAL MEDICATION; ANESTHETIC EFFICACY; DOUBLE-BLIND; SUCCESS RATE; LIDOCAINE; TEETH; ACETAMINOPHEN; PREMEDICATION; ARTICAINE;

D O I：

10.1111/aej.12306

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The aim of this study was to compare preventive ibuprofen administration to placebo on the efficacy of inferior alveolar nerve block in patients with irreversible pulpitis. A search was performed in PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library, SIGLE, and grey literature. The risk of bias was evaluated through the Cochrane Collaboration's tool. The quality of evidence was assessed using the GRADE approach. Only seven studies remained for the meta-analysis. Administering ibuprofen before anaesthesia increased the success rate of injectable anaesthesia (RR = 1.79; 95% confidence interval (CI) 1.32-2.42; P = 0.0002) even in cases of symptomatic irreversible pulpitis (RR = 1.55; 95% CI 1.05-2.29; P = 0.03). The intensity of pain was lower for ibuprofen (standardised difference means (SMD) = -3.73; 95% CI -6.43 to -1.04; P = 0.007). Ibuprofen as premedication is beneficial for the success of inferior alveolar nerve block.

引用

页码：246 / 258

页数：13

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