The semantic connectivity map: an adapting self-organising knowledge discovery method in data bases. Experience in gastro-oesophageal reflux disease

被引:63
作者
Buscema, Massimo [1 ]
Grossi, Enzo [2 ]
机构
[1] Seme Res Ctr Sci Commun, I-00128 Rome, Italy
[2] Dipartimento Farma Italia Bracco SpA, I-20097 Milan, Italy
关键词
AAS; artificial adaptive systems; ANN; artificial neural networks; connectivity map; non-linearity; AutoCM;
D O I
10.1504/IJDMB.2008.022159
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We describe here a new mapping method able to find out connectivity traces among variables thanks to an artificial adaptive system, the Auto Contractive Map (AutoCM), able to define the strength of the associations of each variable with all the others in a dataset. After the training phase, the weights matrix of the AutoCM represents the map of the main connections between the variables. The example of gastro-oesophageal reflux disease data base is extremely useful to figure out how this new approach can help to re-design the overall structure of factors related to complex and specific diseases description.
引用
收藏
页码:362 / 404
页数:43
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