Finite element simulations of laser refractive corneal surgery

被引:66
作者
Pandolfi, Anna [1 ]
Fotia, Giorgio [2 ]
Manganiello, Federico [1 ]
机构
[1] Politecn Milan, Dipartimento Ingn Strutturale, I-20133 Milan, Italy
[2] Sardegna Ric, CRS4 Bioinformat Lab, I-09010 Pula, Italy
关键词
Human cornea; Refractive power; Ablation profiles; Refractive corneal surgery; Finite elements; Fiber reinforced material; PHOTOREFRACTIVE KERATECTOMY; COLLAGEN FIBRILS; ORIENTATION; MYOPIA; MODEL;
D O I
10.1007/s00366-008-0102-5
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
We setup a mechanically based finite element model to evaluate the change in the shape of the human cornea induced by ablation of stromal tissue. By considering the deformability of the cornea, the model computes the change of the dioptric power resulting from ablative laser surgery. We use a previously developed 3-D finite element model of the human cornea (Pandolfi and Manganiello in Biomech Model Mechanobiol 5:237-246, 2006). The solid geometry is discretized into finite elements by an automatic procedure which recovers the unloaded configuration. The geometry is defined in parametric form and can be characterized by individual geometrical data when available. A two-fiber reinforced hyperelastic material model, which accounts for the organization of the anisotropic collagen structure, is adopted to describe the stromal tissue. For the simulation of laser refractive surgery of myopic and astigmatic eyes, a geometrical correction of the corneal profile is included into the code. We show two examples of application of the model to the reshaping of a myopic and an astigmatic eye. Numerical results provide the postoperative shape of the cornea, the corrected refractive power, and the distribution of the stress throughout the stromal tissue.
引用
收藏
页码:15 / 24
页数:10
相关论文
共 27 条
  • [1] Biomechanical modeling of refractive corneal surgery
    Alastrué, V
    Calvo, B
    Peña, E
    Doblaré, M
    [J]. JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 2006, 128 (01): : 150 - 160
  • [2] Application of structural analysis to the mechanical behaviour of the cornea
    Anderson, K
    El-Sheikh, A
    Newson, T
    [J]. JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2004, 1 (01) : 3 - 15
  • [3] [Anonymous], 1997, The eye and visual optical instruments
  • [4] Lamellar orientation in human cornea in relation to mechanical properties
    Boote, C
    Dennis, S
    Huang, YF
    Quantock, AJ
    Meek, KM
    [J]. JOURNAL OF STRUCTURAL BIOLOGY, 2005, 149 (01) : 1 - 6
  • [5] Collagen fibrils appear more closely packed in the prepupillary cornea: Optical and biomechanical implications
    Boote, C
    Dennis, S
    Newton, RH
    Puri, H
    Meek, KM
    [J]. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2003, 44 (07) : 2941 - 2948
  • [6] CANO D, 2001, J OPT SOC AM A, V32, P239
  • [7] Daxer A, 1997, INVEST OPHTH VIS SCI, V38, P121
  • [8] Gatinel D, 2001, INVEST OPHTH VIS SCI, V42, P1736
  • [9] Corneal topography of photorefractive keratectomy versus laser in situ keratomileusis
    Hersh, PS
    Scher, KS
    Irani, R
    [J]. OPHTHALMOLOGY, 1998, 105 (04) : 612 - 619
  • [10] Holzapfel G.A., 2000, Nonlinear Solid Mechanics: A Continuum Approach for Engineering