Molecular docking of C-Jun-N-Terminal Kinase (Jnk) with amino-pyrimidine derivatives

被引：1

作者：

Meenakumari, Krishnamoorthy ^{[1
]}

Bupesh, Giridharan ^{[1
]}

机构：

[1] Sree Balaji Med Coll & Hosp SBMCH, Cent Res Lab, BIHER, Res & Dev Wing, Chennai 600044, Tamil Nadu, India

来源：

BIOINFORMATION | 2020年 / 16卷 / 06期

关键词：

JNK3; inhibitors; amino-pyrimidine; SIGNAL-TRANSDUCTION; PATHWAYS; STRESS;

D O I：

10.6026/97320630016462

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

It is of interest to document the molecular docking of C-Jun-N-Terminal Kinase (Jnk) (known structure with PDB ID: 1PMN) with amino-pyrimidine derivatives in the context of Alzheimer's Disease (AD). We report the optimal binding features (binding energy, interacting residues, inter atomic hydrogen bonding patterns) of 11 amino-pyrimidine derivatives with Jnk for further consideration.

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页码：462 / 467

页数：6

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