Comparison of Low-Dose Oxytocin and Dinoprostone for Labor Induction in Postterm Pregnancies: A Randomized Controlled Prospective Study

被引：9

作者：

Akay, Nezahat Ozturk ^{[1
]}

Hizli, Deniz ^{[1
]}

Yilmaz, Saynur Sarici ^{[1
]}

Yalvac, Serdar ^{[1
]}

Kandemir, Omer ^{[1
]}

机构：

[1] Etlik Zubeyde Hanim Womens Hlth Teaching & Res Ho, Ankara, Turkey

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 2012年 / 73卷 / 03期

关键词：

Postterm pregnancy; Oxytocin; Dinoprostone; Labor induction; TERM PREMATURE RUPTURE; MISOPROSTOL; TRIAL;

D O I：

10.1159/000334404

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Aims: The aim of this study was to compare the efficacy of oxytocin and dinoprostone in achieving successful labor induction and vaginal delivery in postterm women with an unfavorable cervix. Methods: Postterm women with an uncomplicated pregnancy and a Bishop score of <= 6 were randomized to receive either dinoprostone vaginal pessary (Propess (R)) or low-dose oxytocin. The primary outcomes were the length of the induction-to-delivery period and the incidence of vaginal delivery. Results: A total of 144 women were available for the analysis. The overall vaginal delivery rates were 75% (54/72) for the dinoprostone group and 80.6% (58/72; p = 0.35) for the oxytocin group; the mean induction-to-vaginal delivery interval was 13.3 and 10.3 h in the dinoprostone and the oxytocin group, respectively (p = 0.003). Uterine hyperstimulation was 7.4% compared with 6.8% (p = 0.8), and abnormal fetal heart rate was 26.4% compared with 18% (p = 0.2), respectively. Conclusion: Both oxytocin and dinoprostone seem to have similar obstetric outcomes in postterm pregnancies with an unfavorable cervix, except for a significant superiority of oxytocin for delivery in a shorter period. Copyright (C) 2012 S. Karger AG, Basel

引用

页码：242 / 247

页数：6

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