1H NMR relaxation times of skeletal muscle metabolites at 3 T

被引：69
作者：
Krssak, M
Mlynárik, V
Meyerspeer, M
Moser, E
Roden, M
机构：
[1] Univ Vienna, Div Endocrinol & Metab, Dept Internal Med 3, A-1090 Vienna, Austria
[2] Med Univ Vienna, MR Ctr Excellence, Vienna, Austria
[3] Med Univ Vienna, Dept Radiodiag, Vienna, Austria
[4] Med Univ Vienna, Dept Med Phys, Vienna, Austria
来源：
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE | 2004年 / 16卷 / 04期
关键词：
nuclear magnetic resonance spectroscopy; proton; relaxation times; skeletal muscle;
D O I：
10.1007/s10334-003-0029-1
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
This study reports proton relaxation times of water and metabolites in soleus and tibialis anterior muscles of young healthy volunteers at 3 T. The results are in agreement with data reported for 1.5 and 4 T, showing a steady increase of spin-lattice relaxation times of water, creatine and lipids with B-0 and no effect of B-0 on spin-spin relaxation. Comparison between muscles revealed a longer spin-spin relaxation time of water in soleus than in tibialis anterior muscle (31 +/- 1 ms vs. 28 +/- 1 ms, p < 0.05). These data can be applied to relaxation correction for the absolute quantification of skeletal muscle metabolite concentrations and further sequence optimization.
引用
收藏
页码：155 / 159
页数：5
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