Coexistence of Tumid Lupus Erythematosus With Systemic Lupus Erythematosus and Discoid Lupus Erythematosus A Report of Two Cases of Tumid Lupus

被引:20
作者
Stead, Jennifer [2 ]
Headley, Catherine [3 ]
Ioffreda, Michael [3 ]
Kovarik, Carrie [1 ]
Werth, Victoria [1 ,4 ]
机构
[1] Univ Penn, Dept Dermatol, Philadelphia, PA 19104 USA
[2] Philadelphia Coll Osteopath Med, Philadelphia, PA USA
[3] Penn State Milton S Hershey Med Ctr, Coll Med, Hershey, PA USA
[4] Philadelphia VA Hosp, Hershey, PA USA
关键词
tumid lupus erythematosus; systemic lupus erythematosus; discoid lupus erythematosus; chronic cutaneous lupus erythematosus;
D O I
10.1097/RHU.0b013e31817d1183
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Tumid lupus erythematosus (LE) is a rare variant of chronic cutaneous LE that is characterized clinically by smooth, nonscarring, pink to violaceous papules or plaques without evidence of surface change. Histopathologic features include superficial and deep lymphocytic infiltration in a perivascular and periadnexal distribution, with dermal interstitial mucin deposition and focal or absent dermoepidermal junction involvement. These clinical and histopathologic features can be challenging to differentiate from other cutaneous diseases. This is particularly true because patients with tumid LE usually do not have other manifestations of systemic LE or cutaneous LE. We present 2 cases of tumid LE, one associated with concomitant systemic LE and the other occurring concurrently with discoid LE. Furthermore, we demonstrate the rare occurrence of a patient with tumid LE occurring below the waist at a photo-protected site.
引用
收藏
页码:338 / 341
页数:4
相关论文
共 12 条
[1]  
ACKERMAN B, 1997, HISTOLOGIC DIAGNOSIS
[2]   Tumid lupus erythematosus: Criteria for classification with immunohistochemical analysis [J].
Alexiades-Armenakas, MR ;
Baldassano, M ;
Bince, B ;
Werth, V ;
Bystryn, JC ;
Kamino, H ;
Soter, NA ;
Franks, AG .
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2003, 49 (04) :494-500
[3]  
ALEXIADESARMENA.M, DERMATOL ONLINE J, V7, P14
[4]   Lupus tumidus [J].
Dekle, CL ;
Mannes, KD ;
Davis, LS ;
Sangueza, OP .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 41 (02) :250-253
[5]  
Elder D, 2007, ATLAS SYNOPSIS LEVER
[6]  
Gougerot H., 1930, B SOC FR DERMATOL SY, V37, P1291
[7]   Histopathologic findings in lupus erythematosus tumidus: Review of 80 patients [J].
Kuhn, A ;
Sonntag, M ;
Ruzicka, T ;
Lehmann, P ;
Megahed, M .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2003, 48 (06) :901-908
[8]   Lupus erythematosus tumidus - A neglected subset of cutaneous lupus erythematosus: Report of 40 cases [J].
Kuhn, A ;
Richter-Hintz, D ;
Oslislo, C ;
Ruzicka, T ;
Megahed, M ;
Lehmann, P .
ARCHIVES OF DERMATOLOGY, 2000, 136 (08) :1033-1041
[9]   Unilateral tumid lupus erythematosus [J].
Pacheco, TR ;
Spates, ST ;
Lee, LA .
LUPUS, 2002, 11 (06) :388-391
[10]   Chronic cutaneous lupus erythematosus - Clinical spectrum [J].
Pramatarov, KD .
CLINICS IN DERMATOLOGY, 2004, 22 (02) :113-120