N,N-Di- and N,N,C-Trialkylation of α-Sulfoximino Esters

被引：17

作者：

Hata, Shingo ^{[1
]}

Maeda, Tatsuya ^{[1
]}

Shimizu, Makoto ^{[1
]}

机构：

[1] Mie Univ, Grad Sch Engn, Dept Chem Mat, Tsu, Mie 5148507, Japan

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 2012年 / 85卷 / 11期

关键词：

N-ALKYLATION; IMINIUM SALT; STEREOSELECTIVE-SYNTHESIS; NUCLEOPHILIC-ADDITION; STRECKER REACTION; AMINO-ACIDS; DERIVATIVES; DISCOVERY; OXIDATION;

D O I：

10.1246/bcsj.20120195

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N,N-Dialkylation of alpha-sulfoximino esters with Grignard reagents proceeds to give alpha-N,N-dialkylamino esters. N,N,C-Trialkylated product is also obtained via the oxidation and nueleophilic addition reaction of the intermediary enolate.

引用

页码：1203 / 1205

页数：3

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