共 39 条
- [21] Mutant Huntingtin Impairs Pancreatic β-cells by Recruiting IRS-2 and Disturbing the PI3K/AKT/FoxO1 Signaling Pathway in Huntington’s DiseaseJournal of Molecular Neuroscience, 2021, 71 : 2646 - 2658Li Li论文数: 0 引用数: 0 h-index: 0机构: Tongji Medical College,Department of Histology and EmbryologyYun Sun论文数: 0 引用数: 0 h-index: 0机构: Tongji Medical College,Department of Histology and EmbryologyYinong Zhang论文数: 0 引用数: 0 h-index: 0机构: Tongji Medical College,Department of Histology and EmbryologyWeixi Wang论文数: 0 引用数: 0 h-index: 0机构: Tongji Medical College,Department of Histology and EmbryologyCuifang Ye论文数: 0 引用数: 0 h-index: 0机构: Tongji Medical College,Department of Histology and Embryology
- [22] Mutant huntingtin expression in microglia is neither required nor sufficient to cause the Huntington's disease-like phenotype in BACHD miceHUMAN MOLECULAR GENETICS, 2019, 28 (10) : 1661 - 1670Petkau, Terri L.论文数: 0 引用数: 0 h-index: 0机构: Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Childrens & Womens Hosp, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, CanadaHill, Austin论文数: 0 引用数: 0 h-index: 0机构: Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Childrens & Womens Hosp, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, CanadaConnolly, Colum论文数: 0 引用数: 0 h-index: 0机构: Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Childrens & Womens Hosp, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, CanadaLu, Ge论文数: 0 引用数: 0 h-index: 0机构: Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Childrens & Womens Hosp, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, CanadaWagner, Pam论文数: 0 引用数: 0 h-index: 0机构: Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Childrens & Womens Hosp, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, CanadaKosior, Natalia论文数: 0 引用数: 0 h-index: 0机构: Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Childrens & Womens Hosp, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, CanadaBlanco, Jake论文数: 0 引用数: 0 h-index: 0机构: Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Childrens & Womens Hosp, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, CanadaLeavitt, Blair R.论文数: 0 引用数: 0 h-index: 0机构: Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Childrens & Womens Hosp, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada Univ British Columbia Hosp, Dept Med, Div Neurol, S 192-2211 Wesbrook Mall, Vancouver, BC V6T 2B5, Canada Univ British Columbia, Brain Res Ctr, Vancouver, BC V6T 1Z3, Canada Univ British Columbia, Dept Med Genet, Ctr Mol Med & Therapeut, 980 West 28th Ave, Vancouver, BC V5Z 4H4, Canada
- [23] Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in miceHUMAN MOLECULAR GENETICS, 2006, 15 (12) : 2015 - 2024Lloret, Alejandro论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USADragileva, Ella论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USATeed, Allison论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USAEspinola, Janice论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USAFossale, Elisa论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USAGillis, Tammy论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USALopez, Edith论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USAMyers, Richard H.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USAMacDonald, Marcy E.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USAWheeler, Vanessa C.论文数: 0 引用数: 0 h-index: 0机构: Massachusetts Gen Hosp, Ctr Human Genet Res, Mol Neurogenet Unit, Boston, MA 02114 USA
- [24] Elevated plasma and CSF neurofilament light chain concentrations are stabilized in response to mutant huntingtin lowering in the brains of Huntington's disease miceTRANSLATIONAL NEURODEGENERATION, 2024, 13 (01):Caron, Nicholas S.论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada BC Childrens Hosp, Res Inst, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Vancouver, BC V6T 1Z3, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaByrne, Lauren M.论文数: 0 引用数: 0 h-index: 0机构: UCL, Queen Sq Inst Neurol, UCL Huntingtons Dis Ctr, London WC1N 3BG, England Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaLemarie, Fanny L.论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada BC Childrens Hosp, Res Inst, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Vancouver, BC V6T 1Z3, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaBone, Jeffrey N.论文数: 0 引用数: 0 h-index: 0机构: BC Childrens Hosp, Res Inst, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Stat, Vancouver, BC V6T 1Z2, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaAly, Amirah E. -E.论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada BC Childrens Hosp, Res Inst, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Vancouver, BC V6T 1Z3, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaKo, Seunghyun论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaAnderson, Christine论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaCasal, Lorenzo L.论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaHill, Austin M.论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaHawellek, David J.论文数: 0 引用数: 0 h-index: 0机构: F Hoffmann La Roche Ltd, Roche Innovat Ctr Basel, Roche Pharm Res & Early Dev, Grenzacherstr 124, CH-4070 Basel, Switzerland Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaMcColgan, Peter论文数: 0 引用数: 0 h-index: 0机构: Roche Prod Ltd, Welwyn Garden City AL7 1TW, England Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaWild, Edward J.论文数: 0 引用数: 0 h-index: 0机构: UCL, Queen Sq Inst Neurol, UCL Huntingtons Dis Ctr, London WC1N 3BG, England Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaLeavitt, Blair R.论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada BC Childrens Hosp, Res Inst, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Vancouver, BC V6T 1Z3, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaHayden, Michael R.论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada BC Childrens Hosp, Res Inst, Vancouver, BC V5Z 4H4, Canada Univ British Columbia, Dept Med Genet, Vancouver, BC V6T 1Z3, Canada Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada
- [25] Evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease in cell culture and in transgenic mice expressing mutant huntingtinPHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 1999, 354 (1386) : 1047 - 1055Hackam, AS论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaHodgson, JG论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaSingaraja, R论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaZhang, TQ论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaGan, L论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaGutekunst, CA论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaHersch, SM论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, CanadaHayden, MR论文数: 0 引用数: 0 h-index: 0机构: Ctr Mol Med & Therapeut, Vancouver, BC V5Z 4H4, Canada
- [26] Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's DiseaseNeuroscience Bulletin, 2019, 35 (06) : 1024 - 1034Weiqi Yang论文数: 0 引用数: 0 h-index: 0机构: Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan University School of Medical College, Hexi University Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityJingmo Xie论文数: 0 引用数: 0 h-index: 0机构: Department of Anatomy, Histology and Embryology,Zhaoqing Medical College Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityQiang Qiang论文数: 0 引用数: 0 h-index: 0机构: Department of Neurology, Huadong Hospital, FudanUniversity Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityLi Li论文数: 0 引用数: 0 h-index: 0机构: Department of Anesthesiology, Huashan Hospital, FudanUniversity Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityXiang Lin论文数: 0 引用数: 0 h-index: 0机构: Department of Neurology and Institute of Neurology, First Affiliated Hospital, Fujian Medical University Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityYiqing Ren论文数: 0 引用数: 0 h-index: 0机构: Department of Neurology, Huadong Hospital, FudanUniversity Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityWenlei Ren论文数: 0 引用数: 0 h-index: 0机构: Department of Neurology, Huadong Hospital, FudanUniversity Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityQiong Liu论文数: 0 引用数: 0 h-index: 0机构: Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan University Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityGuomin Zhou论文数: 0 引用数: 0 h-index: 0机构: Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan University Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan UniversityWenshi Wei论文数: 0 引用数: 0 h-index: 0机构: Department of Neurology, Huadong Hospital, FudanUniversity Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan University论文数: 引用数: h-index:机构:Lixiang Ma论文数: 0 引用数: 0 h-index: 0机构: Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan University Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences, Fudan University
- [27] Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington’s DiseaseNeuroscience Bulletin, 2019, 35 : 1024 - 1034Weiqi Yang论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesJingmo Xie论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesQiang Qiang论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesLi Li论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesXiang Lin论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesYiqing Ren论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesWenlei Ren论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesQiong Liu论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesGuomin Zhou论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesWenshi Wei论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesHexige Saiyin论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical SciencesLixiang Ma论文数: 0 引用数: 0 h-index: 0机构: Fudan University,Department of Anatomy, Histology and Embryology, School of Basic Medical Sciences
- [28] Gedunin Degrades Aggregates of Mutant Huntingtin Protein and Intranuclear Inclusions via the Proteasomal Pathway in Neurons and Fibroblasts from Patients with Huntington's DiseaseNEUROSCIENCE BULLETIN, 2019, 35 (06) : 1024 - 1034Yang, Weiqi论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R China Hexi Univ, Sch Med Coll, Zhangye 734000, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaXie, Jingmo论文数: 0 引用数: 0 h-index: 0机构: Zhaoqing Med Coll, Dept Anat Histol & Embryol, Zhaoqing 526000, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaQiang, Qiang论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Huadong Hosp, Dept Neurol, Shanghai 200040, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaLi, Li论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Huashan Hosp, Dept Anesthesiol, Shanghai 200040, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaLin, Xiang论文数: 0 引用数: 0 h-index: 0机构: Fujian Med Univ, Dept Neurol, Affiliated Hosp 1, Fuzhou 350005, Fujian, Peoples R China Fujian Med Univ, Inst Neurol, Affiliated Hosp 1, Fuzhou 350005, Fujian, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaRen, Yiqing论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Huadong Hosp, Dept Neurol, Shanghai 200040, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaRen, Wenlei论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Huadong Hosp, Dept Neurol, Shanghai 200040, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaLiu, Qiong论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaZhou, Guomin论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R ChinaWei, Wenshi论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Huadong Hosp, Dept Neurol, Shanghai 200040, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R China论文数: 引用数: h-index:机构:Ma, Lixiang论文数: 0 引用数: 0 h-index: 0机构: Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R China Fudan Univ, Sch Basic Med Sci, Dept Anat Histol & Embryol, Shanghai 200032, Peoples R China
- [29] Elucidation of the role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with mutant huntingtin (mtHtt) for mitochondrial elimination in Huntington's diseaseFASEB JOURNAL, 2015, 29Hwang, Sunhee论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Sch Med, Chem & Syst Biol, Stanford, CA 94305 USA Stanford Univ, Sch Med, Chem & Syst Biol, Stanford, CA 94305 USADisatnik, Marie-HeLene论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Sch Med, Chem & Syst Biol, Stanford, CA 94305 USA Stanford Univ, Sch Med, Chem & Syst Biol, Stanford, CA 94305 USAMochly-Rosen, Daria论文数: 0 引用数: 0 h-index: 0机构: Stanford Univ, Sch Med, Chem & Syst Biol, Stanford, CA 94305 USA Stanford Univ, Sch Med, Chem & Syst Biol, Stanford, CA 94305 USA
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